TEX264 is a major receptor for mammalian reticulophagy.
Autophagy
lysosome
macroautophagy
selective autophagy
stress
Journal
Autophagy
ISSN: 1554-8635
Titre abrégé: Autophagy
Pays: United States
ID NLM: 101265188
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
pubmed:
1
8
2019
medline:
23
2
2020
entrez:
1
8
2019
Statut:
ppublish
Résumé
The endoplasmic reticulum (ER) is the main site of cellular protein and calcium homeostasis, as well as lipid synthesis in eukaryotic cells. Reticulophagy is the selective clearance and degradation of ER components and membranes by the cellular autophagy machinery. Recently, 2 groups (the laboratories of Noboru Mizushima and Wade Harper) independently identified the previously uncharacterized protein TEX264 (testis expressed gene 264) as a major receptor for selective reticulophagy in mammalian cells. Here we highlight and integrate the major findings of their recent work.
Identifiants
pubmed: 31362563
doi: 10.1080/15548627.2019.1646540
pmc: PMC6735500
doi:
Substances chimiques
Carrier Proteins
0
Ccpg1 protein, mouse
0
Cell Cycle Proteins
0
Nerve Tissue Proteins
0
Rtn3 protein, mouse
0
Types de publication
Editorial
Research Support, N.I.H., Extramural
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
1677-1681Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM131919
Pays : United States
Commentaires et corrections
Type : CommentOn
Type : CommentOn
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