Oocyte donation in donors with levonorgestrel intrauterine device: a good match?
Adult
Birth Rate
Cohort Studies
Contraceptive Agents, Female
/ administration & dosage
Female
Humans
Infant, Newborn
Intrauterine Devices, Medicated
Levonorgestrel
/ administration & dosage
Male
Oocyte Donation
/ standards
Pregnancy
Pregnancy Outcome
/ epidemiology
Pregnancy Rate
Retrospective Studies
Tissue Donors
/ statistics & numerical data
Young Adult
Journal
Reproductive biomedicine online
ISSN: 1472-6491
Titre abrégé: Reprod Biomed Online
Pays: Netherlands
ID NLM: 101122473
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
25
02
2019
revised:
24
04
2019
accepted:
31
05
2019
pubmed:
1
8
2019
medline:
21
8
2020
entrez:
1
8
2019
Statut:
ppublish
Résumé
Does the levonorgestrel-releasing intrauterine device (LNG-IUD) influence cumulative live birth rate (CLBR) in oocyte donor cycles? Retrospective cohort study based on prospectively collected data from 1 May 2009 to 31 December 2017, without attrition, consisting of 491 consecutive cycles of vitrified oocyte donation, none lost to follow-up (unique donor-recipient pairs). All donors underwent ovarian stimulation using gonadotrophin releasing hormone (GnRH) antagonist co-treatment and GnRH agonist trigger. CLBR was chosen as primary outcome measure. In total, 103 (21.0%) cycles were carried out in donors carrying a LNG-IUD. In 388 (79.0%) cycles, no LNG-IUD was present. After confounder-adjustment, the use of an LNG-IUD did not have a statistically significant influence on CLBR. The LNG-IUD does not negatively affect CLBR.
Identifiants
pubmed: 31362915
pii: S1472-6483(19)30586-3
doi: 10.1016/j.rbmo.2019.05.022
pii:
doi:
Substances chimiques
Contraceptive Agents, Female
0
Levonorgestrel
5W7SIA7YZW
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
641-647Informations de copyright
Copyright © 2019 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.