Impact of gastroesophageal reflux disease on the quality of life of Polish patients.
Gastroesophageal reflux disease
Health-related quality of life
Obesity
Psychological factors
Stress
Journal
World journal of clinical cases
ISSN: 2307-8960
Titre abrégé: World J Clin Cases
Pays: United States
ID NLM: 101618806
Informations de publication
Date de publication:
26 Jun 2019
26 Jun 2019
Historique:
received:
03
01
2019
revised:
22
04
2019
accepted:
02
05
2019
entrez:
1
8
2019
pubmed:
1
8
2019
medline:
1
8
2019
Statut:
ppublish
Résumé
Gastro-esophageal reflux disease (GERD) is a serious health and social problem leading to a considerable decrease in the quality of life of patients. Among the risk factors associated with reflux symptoms and that decrease the quality of life are stress, overweight and an increase in body weight. The concept of health-related quality of life (HRQL) covers an expanded effect of the disease on a patient's wellbeing and daily activities and is one of the measures of widely understood quality of life. HRQL is commonly measured using a self-administered, disease-specific questionnaires. To determine the effect of reflux symptoms, stress and body mass index (BMI) on the quality of life. The study included 118 patients diagnosed with reflux disease who reported to an outpatient department of gastroenterology or a specialist hospital ward for planned diagnostic tests. Assessment of the level of reflux was based on the frequency of 5 typical of GERD symptoms. HRQL was measured by a 36-item Short Form Health Survey (SF-36) and level of stress using the 10-item Perceived Stress Scale. Multi-variable relationships were analyzed using multiple regression. Eleven models of analysis were performed in which the scale of the SF-36 was included as an explained variable. In all models, the same set of explanatory variables: Gender, age, reflux symptoms, stress and BMI, were included. The frequency of GERD symptoms resulted in a decrease in patients' results according to 6 out of 8 SF-36 scales- except for mental health and vitality scales. Stress resulted in a decrease in patient function in all domains measured using the SF-36. Age resulted in a decrease in physical function and in overall assessment of self-reported state of health. An increasing BMI exerted a negative effect on physical fitness and limitations in functioning resulting from this decrease. In GERD patients, HRQL is negatively determined by the frequency of reflux symptoms and by stress, furthermore an increasing BMI and age decreases the level of physical function.
Sections du résumé
BACKGROUND
BACKGROUND
Gastro-esophageal reflux disease (GERD) is a serious health and social problem leading to a considerable decrease in the quality of life of patients. Among the risk factors associated with reflux symptoms and that decrease the quality of life are stress, overweight and an increase in body weight. The concept of health-related quality of life (HRQL) covers an expanded effect of the disease on a patient's wellbeing and daily activities and is one of the measures of widely understood quality of life. HRQL is commonly measured using a self-administered, disease-specific questionnaires.
AIM
OBJECTIVE
To determine the effect of reflux symptoms, stress and body mass index (BMI) on the quality of life.
METHODS
METHODS
The study included 118 patients diagnosed with reflux disease who reported to an outpatient department of gastroenterology or a specialist hospital ward for planned diagnostic tests. Assessment of the level of reflux was based on the frequency of 5 typical of GERD symptoms. HRQL was measured by a 36-item Short Form Health Survey (SF-36) and level of stress using the 10-item Perceived Stress Scale. Multi-variable relationships were analyzed using multiple regression.
RESULTS
RESULTS
Eleven models of analysis were performed in which the scale of the SF-36 was included as an explained variable. In all models, the same set of explanatory variables: Gender, age, reflux symptoms, stress and BMI, were included. The frequency of GERD symptoms resulted in a decrease in patients' results according to 6 out of 8 SF-36 scales- except for mental health and vitality scales. Stress resulted in a decrease in patient function in all domains measured using the SF-36. Age resulted in a decrease in physical function and in overall assessment of self-reported state of health. An increasing BMI exerted a negative effect on physical fitness and limitations in functioning resulting from this decrease.
CONCLUSION
CONCLUSIONS
In GERD patients, HRQL is negatively determined by the frequency of reflux symptoms and by stress, furthermore an increasing BMI and age decreases the level of physical function.
Identifiants
pubmed: 31363470
doi: 10.12998/wjcc.v7.i12.1421
pmc: PMC6656664
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1421-1429Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Références
J Epidemiol Community Health. 1999 Jan;53(1):46-50
pubmed: 10326053
Am J Med. 1999 Jun;106(6):642-9
pubmed: 10378622
Gut. 1999 Apr;44 Suppl 2:S1-16
pubmed: 10741335
Scand J Gastroenterol. 2001 Aug;36(8):800-5
pubmed: 11495073
J Am Soc Nephrol. 2001 Dec;12(12):2797-806
pubmed: 11729250
Med Care. 2002 Sep;40(9):761-70
pubmed: 12218767
Eur Respir J. 2003 Apr;21(4):682-7
pubmed: 12762357
JAMA. 2003 Jul 2;290(1):66-72
pubmed: 12837713
Health Qual Life Outcomes. 2003 Nov 29;1:73
pubmed: 14641914
Rom J Gastroenterol. 2005 Jun;14(2):117-21
pubmed: 15990929
Ann Intern Med. 2005 Aug 2;143(3):199-211
pubmed: 16061918
Scand J Gastroenterol. 2005 Jul;40(7):759-67
pubmed: 16118911
J Am Board Fam Pract. 2005 Sep-Oct;18(5):393-400
pubmed: 16148249
J Psychosom Res. 2005 Dec;59(6):415-24
pubmed: 16310024
N Engl J Med. 2006 Jun 1;354(22):2340-8
pubmed: 16738270
Am J Gastroenterol. 2006 Aug;101(8):1900-20; quiz 1943
pubmed: 16928254
Gut. 2007 Sep;56(9):1191-7
pubmed: 17272649
Respiration. 2008;75(4):393-401
pubmed: 17596681
Aliment Pharmacol Ther. 2007 Sep 1;26(5):683-91
pubmed: 17697202
Aliment Pharmacol Ther. 2008 Mar 15;27(6):473-82
pubmed: 18194508
Dig Dis Sci. 2008 Sep;53(9):2307-12
pubmed: 18651221
Am J Gastroenterol. 2008 Aug;103(8):2111-22
pubmed: 18796104
Maturitas. 2009 Jan 20;62(1):85-90
pubmed: 19100693
Scand J Gastroenterol. 2010;45(1):21-9
pubmed: 19961344
BMJ. 2016 Mar 08;352:i582
pubmed: 26956984
Am J Med. 1998 Mar;104(3):252-8
pubmed: 9552088
Am J Public Health. 1998 Dec;88(12):1814-20
pubmed: 9842379