Cerebral Autoregulation Is Impaired During Deep Hypothermia-A Porcine Multimodal Neuromonitoring Study.

animal study brain oxygenation cerebral autoregulation deep hypothermia multimodal neuromonitoring

Journal

Therapeutic hypothermia and temperature management
ISSN: 2153-7933
Titre abrégé: Ther Hypothermia Temp Manag
Pays: United States
ID NLM: 101543518

Informations de publication

Date de publication:
Jun 2020
Historique:
pubmed: 1 8 2019
medline: 29 10 2021
entrez: 1 8 2019
Statut: ppublish

Résumé

Effects of brain temperature modulation on cerebral hemodynamics are unclear. We aimed at investigating changes of dynamic cerebral autoregulation (AR) indices during induction of deep hypothermia (HT) in a porcine model mimicking the clinical scenario of accidental HT. Thirteen pigs were surface-cooled to a core temperature of 28°C. High-frequency monitoring included brain temperature, mean arterial blood pressure (MAP), intracranial pressure (ICP), brain tissue oxygen tension (P

Identifiants

pubmed: 31364946
doi: 10.1089/ther.2019.0009
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

122-127

Auteurs

Max Gaasch (M)

Neuro-Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Gabriel Putzer (G)

Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Alois J Schiefecker (AJ)

Neuro-Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Judith Martini (J)

Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Giacomo Strapazzon (G)

Institute of Mountain Emergency Medicine, European Academy (EURAC) Research, Bolzano, Italy.

Bogdan Ianosi (B)

Neuro-Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Claudius Thome (C)

Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria.

Peter Paal (P)

Department of Anaesthesiology and Intensive Care Medicine, Hospital of the Brothers of St. John of God Salzburg, Salzburg, Austria.

Hermann Brugger (H)

Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Institute of Mountain Emergency Medicine, European Academy (EURAC) Research, Bolzano, Italy.

Peter Mair (P)

Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Raimund Helbok (R)

Neuro-Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

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Classifications MeSH