Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis.
Astrocytes
EAE
Optic neuritis
Retinal ganglion cells
Journal
Acta neuropathologica communications
ISSN: 2051-5960
Titre abrégé: Acta Neuropathol Commun
Pays: England
ID NLM: 101610673
Informations de publication
Date de publication:
31 07 2019
31 07 2019
Historique:
received:
24
05
2019
accepted:
06
07
2019
entrez:
2
8
2019
pubmed:
2
8
2019
medline:
24
6
2020
Statut:
epublish
Résumé
The animal model experimental autoimmune encephalomyelitis (EAE) has been used extensively in the past to test mechanisms that target peripheral immune cells for treatment of multiple sclerosis (MS). While there have been some notable successes in relapsing MS, the development of therapies for progressive multiple sclerosis (MS) has been hampered by lack of an appropriate animal model. Further, the mechanisms underlying CNS inflammation and neuronal injury remain incompletely elucidated. It is known that the MOG
Identifiants
pubmed: 31366377
doi: 10.1186/s40478-019-0767-6
pii: 10.1186/s40478-019-0767-6
pmc: PMC6670238
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
125Subventions
Organisme : NINDS NIH HHS
ID : P30 NS050274
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007309
Pays : United States
Organisme : NINDS NIH HHS
ID : R37 NS041435
Pays : United States
Organisme : NIH HHS
ID : NS-R37041435
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS041435
Pays : United States
Références
Acta Neuropathol. 2017 Feb;133(2):223-244
pubmed: 27766432
Nature. 2017 Jan 26;541(7638):481-487
pubmed: 28099414
J Neuroimmunol. 2008 Aug 13;199(1-2):83-93
pubmed: 18582952
Acta Neuropathol Commun. 2014 May 09;2:53
pubmed: 24887075
Nat Med. 2005 Feb;11(2):146-52
pubmed: 15665833
J Exp Med. 2017 Feb;214(2):297-307
pubmed: 28057805
J Immunol. 2013 Aug 1;191(3):1006-10
pubmed: 23817414
Mult Scler. 2019 Apr;25(4):532-540
pubmed: 29485352
J Neuropathol Exp Neurol. 2002 Jan;61(1):23-32
pubmed: 11829341
JAMA Neurol. 2013 Jan;70(1):34-43
pubmed: 23318513
Lancet Neurol. 2017 Oct;16(10):797-812
pubmed: 28920886
Nat Med. 2018 Jul;24(7):931-938
pubmed: 29892066
Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3388-93
pubmed: 12882786
BMC Res Notes. 2010 Mar 01;3:50
pubmed: 20193075
PLoS One. 2011;6(8):e22947
pubmed: 21853058
Brain Pathol. 2017 Nov;27(6):737-747
pubmed: 27706868
Ann Neurol. 2015 Jun;77(6):1007-26
pubmed: 25727254
Ann Neurol. 2015 Nov;78(5):801-13
pubmed: 26190464
Neurol Clin. 2011 May;29(2):293-308
pubmed: 21439442
J Neuroimmunol. 2016 Sep 15;298:32-41
pubmed: 27609273
Methods Mol Biol. 2012;814:93-104
pubmed: 22144302
J Neuroinflammation. 2013 Oct 04;10:120
pubmed: 24090415
Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E302-E309
pubmed: 29279367
Handb Clin Neurol. 2014;122:173-89
pubmed: 24507518
Ann Neurol. 2011 Mar;69(3):445-54
pubmed: 21446020
Brain. 2012 Feb;135(Pt 2):521-33
pubmed: 22006982
PLoS One. 2015 Apr 02;10(4):e0122048
pubmed: 25835709
PLoS One. 2010 Aug 24;5(8):e12387
pubmed: 20808778
Exp Eye Res. 2008 Sep;87(3):208-13
pubmed: 18653182
Mol Brain. 2014 Aug 13;7:53
pubmed: 25116810
Glia. 2014 Mar;62(3):452-67
pubmed: 24357067
Mol Vis. 2016 Apr 11;22:332-41
pubmed: 27122964
Brain. 2011 Feb;134(Pt 2):518-33
pubmed: 21252110
Expert Opin Drug Saf. 2017 Aug;16(8):963-972
pubmed: 28641055
Glia. 2017 Feb;65(2):264-277
pubmed: 27778395
J Neurosci. 2009 Sep 16;29(37):11511-22
pubmed: 19759299
Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3606-13
pubmed: 12882814
Lancet Neurol. 2016 May;15(6):574-84
pubmed: 27011339
Nature. 2018 May;557(7707):724-728
pubmed: 29769726
J Immunol. 2011 Jun 1;186(11):6521-31
pubmed: 21515788
Acta Neuropathol Commun. 2019 Mar 25;7(1):48
pubmed: 30909963
Eur J Neurosci. 2004 Jul;20(2):467-73
pubmed: 15233755
Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):965-70
pubmed: 22219359
Ann Neurol. 2018 Jan;83(1):131-141
pubmed: 29283442
Acta Neuropathol Commun. 2018 May 3;6(1):36
pubmed: 29724241
Front Neurol. 2011 Aug 02;2:50
pubmed: 21852980
Mult Scler. 2006 Oct;12(5):526-32
pubmed: 17086896
N Engl J Med. 1992 Feb 27;326(9):581-8
pubmed: 1734247
J Neuroinflammation. 2016 Jun 22;13(1):161
pubmed: 27333900
J Neurol. 2012 Oct;259(10):2119-30
pubmed: 22418995
Mult Scler. 2011 Dec;17(12):1449-63
pubmed: 21865411
Acta Neuropathol. 2019 May;137(5):757-783
pubmed: 30847559
Invest Ophthalmol Vis Sci. 2012 Jan 20;53(1):157-63
pubmed: 22131393
Acta Neuropathol. 1989;77(5):472-9
pubmed: 2497621