High-signal-intensity MR Image in the Hepatobiliary Phase Predicts Long-term Survival in Patients With Hepatocellular Carcinoma.
Aged
Aged, 80 and over
Biliary Tract
/ diagnostic imaging
Carcinoma, Hepatocellular
/ diagnostic imaging
Contrast Media
/ administration & dosage
Disease-Free Survival
Female
Gadolinium DTPA
/ administration & dosage
Humans
Liver Neoplasms
/ diagnostic imaging
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Recurrence, Local
/ diagnostic imaging
Retrospective Studies
Gd-EOB-DTPA-enhanced MRI
Hepatocellular carcinoma
high-signal-intensity
surgical outcome
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
16
05
2019
revised:
17
06
2019
accepted:
19
06
2019
entrez:
2
8
2019
pubmed:
2
8
2019
medline:
8
8
2019
Statut:
ppublish
Résumé
The aim of the study was to evaluate surgical outcomes of patients with high-signal intensity (SI) image hepatocellular carcinoma (HCC). Between 2008 and 2013, 257 HCC patients were retrospectively evaluated. A total of 21 patients were diagnosed as high-SI image HCC, 215 as low-SI image HCC, and 21 patients as mixed (high and low)-SI image HCC in the hepatobiliary (HB) phase of MRI. Five-year overall survival (OS) and recurrence-free survival (RFS) were compared among patient groups. The 5-year OS and RFS rates were significantly higher in patients with high-SI image HCC (100% and 56%) than in patients with low-SI image HCC (71%; p=0.097 and 38%; p=0.0209) and in patients with mixed-SI image HCC (73%; p=0.0329 and 9%; p=0.0021). High-SI image was an independent prognostic factor for OS (relative risk 0.167, p=0.0178) and RFS (relative risk 0.471, p=0.0322) on multivariate analysis. Patients with high-SI image HCC showed favorable long-term survival after curative surgery.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
The aim of the study was to evaluate surgical outcomes of patients with high-signal intensity (SI) image hepatocellular carcinoma (HCC).
PATIENTS AND METHODS
METHODS
Between 2008 and 2013, 257 HCC patients were retrospectively evaluated. A total of 21 patients were diagnosed as high-SI image HCC, 215 as low-SI image HCC, and 21 patients as mixed (high and low)-SI image HCC in the hepatobiliary (HB) phase of MRI. Five-year overall survival (OS) and recurrence-free survival (RFS) were compared among patient groups.
RESULTS
RESULTS
The 5-year OS and RFS rates were significantly higher in patients with high-SI image HCC (100% and 56%) than in patients with low-SI image HCC (71%; p=0.097 and 38%; p=0.0209) and in patients with mixed-SI image HCC (73%; p=0.0329 and 9%; p=0.0021). High-SI image was an independent prognostic factor for OS (relative risk 0.167, p=0.0178) and RFS (relative risk 0.471, p=0.0322) on multivariate analysis.
CONCLUSION
CONCLUSIONS
Patients with high-SI image HCC showed favorable long-term survival after curative surgery.
Identifiants
pubmed: 31366509
pii: 39/8/4219
doi: 10.21873/anticanres.13583
doi:
Substances chimiques
Contrast Media
0
Gadolinium DTPA
K2I13DR72L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4219-4225Informations de copyright
Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.