Broken heart: A matter of the endoplasmic reticulum stress bad management?
Apoptosis
Autophagy
Endoplasmic reticulum stress
Heart complications
Inflammation
Journal
World journal of cardiology
ISSN: 1949-8462
Titre abrégé: World J Cardiol
Pays: United States
ID NLM: 101537090
Informations de publication
Date de publication:
26 Jun 2019
26 Jun 2019
Historique:
received:
23
02
2019
revised:
29
04
2019
accepted:
12
06
2019
entrez:
2
8
2019
pubmed:
2
8
2019
medline:
2
8
2019
Statut:
ppublish
Résumé
Cardiovascular diseases are the number one cause of morbidity and mortality in the United States and worldwide. The induction of the endoplasmic reticulum (ER) stress, a result of a disruption in the ER homeostasis, was found to be highly associated with cardiovascular diseases such as hypertension, diabetes, ischemic heart diseases and heart failure. This review will discuss the latest literature on the different aspects of the involvement of the ER stress in cardiovascular complications and the potential of targeting the ER stress pathways as a new therapeutic approach for cardiovascular complications.
Identifiants
pubmed: 31367278
doi: 10.4330/wjc.v11.i6.159
pmc: PMC6658386
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
159-170Déclaration de conflit d'intérêts
Conflict-of-interest statement: None
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