Randomised trial of cord clamping at very preterm birth: outcomes at 2 years.
neonatal care with cord intact
outcomes at 2 years corrected age
Journal
Archives of disease in childhood. Fetal and neonatal edition
ISSN: 1468-2052
Titre abrégé: Arch Dis Child Fetal Neonatal Ed
Pays: England
ID NLM: 9501297
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
24
01
2019
revised:
15
07
2019
accepted:
17
07
2019
pubmed:
3
8
2019
medline:
6
5
2020
entrez:
3
8
2019
Statut:
ppublish
Résumé
To report outcomes at 2 years corrected age for children of women recruited to a trial comparing alternative policies for timing of cord clamping and immediate neonatal care at very preterm birth. Parallel group randomised (1:1) trial. Eight UK tertiary maternity units. Two hundred and seventy-six babies born to 261 women expected to have a live birth before 32 Deferred cord clamping (≥2 min) and immediate neonatal care with cord intact or immediate (≤20 s) clamping and immediate neonatal care after clamping. Composite of death or adverse neurodevelopmental outcome at 2 years corrected age. Six babies born after 35 Deferred clamping and immediate neonatal care with cord intact may reduce the risk of death or adverse neurodevelopmental outcome at 2 years of age for children born very premature. Confirmation in larger studies is needed to determine the real benefits and harms. ISRCTN21456601.
Identifiants
pubmed: 31371434
pii: archdischild-2019-316912
doi: 10.1136/archdischild-2019-316912
pmc: PMC7363783
doi:
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
292-298Subventions
Organisme : Department of Health
ID : RP-PG-0609-10107
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: JD reports grants from NIHR during the conduct of the trial; LD reports memberships to CTUs funded by NIHR. All other authors have nothing to disclose.
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