A role for S-nitrosylation of the SUMO-conjugating enzyme SCE1 in plant immunity.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
20 08 2019
Historique:
pubmed: 3 8 2019
medline: 24 3 2020
entrez: 3 8 2019
Statut: ppublish

Résumé

SUMOylation, the covalent attachment of the small ubiquitin-like modifier (SUMO) to target proteins, is emerging as a key modulator of eukaryotic immune function. In plants, a SUMO1/2-dependent process has been proposed to control the deployment of host defense responses. The molecular mechanism underpinning this activity remains to be determined, however. Here we show that increasing nitric oxide levels following pathogen recognition promote S-nitrosylation of the

Identifiants

pubmed: 31371496
pii: 1900052116
doi: 10.1073/pnas.1900052116
pmc: PMC6708345
doi:

Substances chimiques

Arabidopsis Proteins 0
SUM2 protein, Arabidopsis 0
Nitric Oxide 31C4KY9ESH
Ubiquitin-Conjugating Enzymes EC 2.3.2.23
At1g09730 protein, Arabidopsis EC 3.4.22.-
Cysteine Endopeptidases EC 3.4.22.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

17090-17095

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/H000984/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/DO11809/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/F017073/1
Pays : United Kingdom

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Michael J Skelly (MJ)

Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom.

Saad I Malik (SI)

Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom.

Thierry Le Bihan (T)

Centre for Synthetic and Systems Biology, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom.

Yuan Bo (Y)

Key Laboratory of Biotechnology, Jiangsu Normal University, Xuzhou 22116, China.

Jihong Jiang (J)

Key Laboratory of Biotechnology, Jiangsu Normal University, Xuzhou 22116, China.
Jiangsu Normal University-Edinburgh University Centre for Transformative Medicinal and Food Plant Biotechnology, Jiangsu Normal University, Xuzhou 22116, China.

Steven H Spoel (SH)

Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom.

Gary J Loake (GJ)

Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom; gloake@ed.ac.uk.
Centre for Synthetic and Systems Biology, University of Edinburgh, EH9 3BF Edinburgh, United Kingdom.
Jiangsu Normal University-Edinburgh University Centre for Transformative Medicinal and Food Plant Biotechnology, Jiangsu Normal University, Xuzhou 22116, China.

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