Effects of metformin on tumor hypoxia and radiotherapy efficacy: a [
CT
Cancer
Hypoxia
Imaging biomarker
Metformin
PET
Radiotherapy
[18F]HX4
Journal
EJNMMI research
ISSN: 2191-219X
Titre abrégé: EJNMMI Res
Pays: Germany
ID NLM: 101560946
Informations de publication
Date de publication:
02 Aug 2019
02 Aug 2019
Historique:
received:
07
05
2019
accepted:
23
07
2019
entrez:
4
8
2019
pubmed:
4
8
2019
medline:
4
8
2019
Statut:
epublish
Résumé
In a colorectal cancer xenograft model, we investigated the therapeutic effect of metformin on tumor hypoxia with [ Colo205-bearing mice (n = 40) underwent a baseline [ [ Metformin decreased [
Sections du résumé
BACKGROUND
BACKGROUND
In a colorectal cancer xenograft model, we investigated the therapeutic effect of metformin on tumor hypoxia with [
METHODS
METHODS
Colo205-bearing mice (n = 40) underwent a baseline [
RESULTS
RESULTS
[
CONCLUSIONS
CONCLUSIONS
Metformin decreased [
Identifiants
pubmed: 31375940
doi: 10.1186/s13550-019-0543-4
pii: 10.1186/s13550-019-0543-4
pmc: PMC6677842
doi:
Types de publication
Journal Article
Langues
eng
Pagination
74Subventions
Organisme : Flanders Innovation & Entrepreneurship (VLAIO)
ID : Baekeland fellowship no 140775
Organisme : Research Foundation Flanders (FWO)
ID : Fellowship no 11ZF116N
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