Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome.

Airways Alveolar hemorrhage Antiphospholipid syndrome Interstitial lung disease Pleuritis Pulmonary embolism Pulmonary hypertension Systemic lupus erythematosus

Journal

Clinics in chest medicine
ISSN: 1557-8216
Titre abrégé: Clin Chest Med
Pays: United States
ID NLM: 7907612

Informations de publication

Date de publication:
09 2019
Historique:
entrez: 5 8 2019
pubmed: 5 8 2019
medline: 31 3 2020
Statut: ppublish

Résumé

Systemic lupus erythematosus (SLE) is a systemic inflammatory disease, characterized by an antibody response to nucleic antigens and involvement of any organ system. Pulmonary manifestations are frequent and include pleuritis, acute lupus pneumonitis, chronic interstitial lung disease, alveolar hemorrhage, shrinking lung syndrome, airway disease, pulmonary hypertension (PH), and thromboembolic disease. The antiphospholipid antibody syndrome (APLAS) is a systemic autoimmune disorder where different prothrombotic factors interact to induce arterial and venous thrombosis. The most common pulmonary manifestations are pulmonary thromboembolism and PH. This review will focus on the clinical presentation, diagnosis, and management of the SLE- and APLAS-associated pulmonary conditions.

Identifiants

pubmed: 31376888
pii: S0272-5231(19)30042-5
doi: 10.1016/j.ccm.2019.06.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

519-529

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Maria Kokosi (M)

Interstitial Lung Disease Unit, Royal Brompton Hospital & Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK; Interstitial Lung Disease Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK. Electronic address: m.kokosi@rbht.nhs.uk.

Boris Lams (B)

Interstitial Lung Disease Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK.

Sangita Agarwal (S)

Interstitial Lung Disease Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK; Rheumatology Department, Guy's and St Thomas' Hospital NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK.

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Classifications MeSH