In silico, in vitro and in vivo analysis of putative virulence factors identified in large clostridial toxin-negative, binary toxin- producing C. difficile strains.

Animals Bacterial Proteins / genetics Bacterial Toxins / biosynthesis Clostridioides difficile / classification Clostridium Infections / microbiology Computational Biology Disease Models, Animal Humans Hydrolysis Mice Proteomics Ribotyping Virulence Virulence Factors / biosynthesis
A(−)B(-)CDT(+) Binary toxin C. difficile Ribotype Virulence

Journal

Anaerobe
ISSN: 1095-8274
Titre abrégé: Anaerobe
Pays: England
ID NLM: 9505216

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 30 04 2019
revised: 28 07 2019
accepted: 31 07 2019
pubmed: 5 8 2019
medline: 21 4 2020
entrez: 5 8 2019
Statut: ppublish

Résumé

The relevance of large clostridial toxin-negative, binary toxin-producing (A

Identifiants

DOI: 10.1016/j.anaerobe.2019.102083 PMID: 31377188
pubmed: 31377188
pii: S1075-9964(19)30143-X
doi: 10.1016/j.anaerobe.2019.102083
pii:
doi:

Substances chimiques

Bacterial Proteins 0
Bacterial Toxins 0
Virulence Factors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102083

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

G O Androga (GO)

The University of Western Australia, School of Biomedical Sciences, Western Australia, Australia; PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Western Australia, Australia.

D R Knight (DR)

Murdoch University, Medical, Molecular and Forensic Sciences, Western Australia, Australia.

M L Hutton (ML)

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.

S J Mileto (SJ)

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.

M L James (ML)

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.

C Evans (C)

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.

D Lyras (D)

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.

B J Chang (BJ)

The University of Western Australia, School of Biomedical Sciences, Western Australia, Australia.

N F Foster (NF)

Department of Health, Communicable Disease Control Directorate, Western Australia, Australia.

T V Riley (TV)

The University of Western Australia, School of Biomedical Sciences, Western Australia, Australia; PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Western Australia, Australia; Murdoch University, Medical, Molecular and Forensic Sciences, Western Australia, Australia; Edith Cowan University, School of Medical and Health Sciences, Western Australia, Australia. Electronic address: thomas.riley@uwa.edu.au.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Toxines bactériennes › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Bactéries › Firmicutes › Clostridiales › Clostridioides › Clostridium difficile › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Infections bactériennes à Gram positif › Infections à Clostridium › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Phénomènes chimiques › Hydrolyse › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Protéomique › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ribotypage › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Phénomènes microbiologiques › Virulence › In silico, in vitro and in vivo analysis of...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Facteurs de virulence › In silico, in vitro and in vivo analysis of...