Comparison of Rest to Aerobic Exercise and Placebo-like Treatment of Acute Sport-Related Concussion in Male and Female Adolescents.
Adolescent
Brain concussion
Exercise
Exercise test
Post-concussion syndrome
Rehabilitation
Journal
Archives of physical medicine and rehabilitation
ISSN: 1532-821X
Titre abrégé: Arch Phys Med Rehabil
Pays: United States
ID NLM: 2985158R
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
11
04
2019
revised:
10
06
2019
accepted:
15
07
2019
pubmed:
5
8
2019
medline:
14
4
2020
entrez:
5
8
2019
Statut:
ppublish
Résumé
To compare a sample of adolescents with sport-related concussion (SRC) who were prescribed rest with 2 arms of a randomized controlled trial comparing aerobic exercise with placebo-like stretching. We also compared sex differences across the 3 approaches to treatment. Quasi-experimental trial. University concussion management clinics. Adolescent athletes (aged 13-18 years) presenting within 10 days of SRC (mean, 5 days after injury) received a recommendation for rest (rest group [RG], n=48, 15.4±1y, 25% female). Their outcomes were compared with matched samples of adolescents assigned to aerobic exercise (exercise group [EG], n=52, 15.3±2y, 46% female) or placebo-like stretching (placebo group [PG], n=51, 15.4±2y, 47% female) (N=151). The primary outcome was median days from injury to recovery. The secondary outcome was proportion classified as normal recovery (<30d) or delayed recovery (≥30d). The RG recovered in 16 days (interquartile range, 9.25-23.25d), which was significantly delayed (P=.020) compared with EG (13d; interquartile range, 10-18.5d). The PG recovered in 17 days (interquartile range, 13-23d). Four percent of the EG, 14% of the PG, and 13% of the RG had delayed recovery (P=.190). There was no difference in recovery time or delayed recovery between male participants and female participants across groups. Female participants prescribed rest experienced an increase in symptoms vs the other groups (P=.013). Relative rest and a placebo-like stretching program were very similar in days to recovery and symptom improvement pattern after SRC. Both conditions were less effective than subsymptom threshold aerobic exercise. Female adolescents appear to be susceptible to symptom increase when prescribed rest.
Identifiants
pubmed: 31377190
pii: S0003-9993(19)30505-2
doi: 10.1016/j.apmr.2019.07.003
pmc: PMC6879855
mid: NIHMS1538432
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT02714192', 'NCT02710123']
Types de publication
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2267-2275Subventions
Organisme : NINDS NIH HHS
ID : R01 NS094444
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001412
Pays : United States
Informations de copyright
Copyright © 2019 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Références
J Athl Train. 2001 Sep;36(3):253-256
pubmed: 12937493
J Head Trauma Rehabil. 2013 Jul-Aug;28(4):241-9
pubmed: 23249769
Br J Sports Med. 2018 Sep;52(18):1179-1190
pubmed: 28735282
Pers Individ Dif. 2013 Aug;55(4):367-374
pubmed: 24089583
Neuroscience. 2004;125(1):129-39
pubmed: 15051152
Am J Sports Med. 2016 Sep;44(9):2276-85
pubmed: 27281276
Psychol Health. 2013;28(9):1032-45
pubmed: 23531274
Br J Sports Med. 2017 Jun;51(12):930-934
pubmed: 28341726
Pediatrics. 2015 Feb;135(2):213-23
pubmed: 25560444
Br J Sports Med. 2017 Jun;51(12):941-948
pubmed: 28566342
Clin Pediatr (Phila). 2013 May;52(5):397-402
pubmed: 23447397
Br J Sports Med. 2009 May;43 Suppl 1:i76-90
pubmed: 19433429
Clin J Sport Med. 2021 Jan;31(1):7-14
pubmed: 30418219
J Pediatr. 2012 Nov;161(5):922-6
pubmed: 22622050
Brain Inj. 2016;30(2):132-45
pubmed: 26671602
J Neural Transm (Vienna). 2011 Sep;118(9):1263-72
pubmed: 21442353
Clin Pediatr (Phila). 2016 Jul;55(8):771-5
pubmed: 26378093
Appl Neuropsychol. 2006;13(3):166-74
pubmed: 17361669
Br J Sports Med. 2017 Jun;51(12):949-957
pubmed: 28455361
Clin J Sport Med. 2020 Sep;30(5):513-517
pubmed: 30418199
Neurosurgery. 2016 Feb;78(2):232-41
pubmed: 26445375
J Head Trauma Rehabil. 2016 May-Jun;31(3):215-24
pubmed: 26098254
Brain Sci. 2017 Aug 11;7(8):
pubmed: 28800081
Br J Sports Med. 2013 Apr;47(5):304-7
pubmed: 23479489
J Neural Transm (Vienna). 2011 Feb;118(2):193-202
pubmed: 20924619
JAMA. 2016 Dec 20;316(23):2504-2514
pubmed: 27997652
Curr Sports Med Rep. 2018 Aug;17(8):262-270
pubmed: 30095546
Clin J Sport Med. 2018 Jan;28(1):13-20
pubmed: 29257777
Front Neurol. 2019 Apr 24;10:395
pubmed: 31105634
Brain Inj. 2015;29(1):58-63
pubmed: 25279423
Br J Sports Med. 2002 Feb;36(1):6-10
pubmed: 11867482
Br J Sports Med. 2013 Apr;47(5):289-93
pubmed: 23479486
PM R. 2011 Oct;3(10 Suppl 2):S359-68
pubmed: 22035678
NeuroRehabilitation. 2007;22(3):199-205
pubmed: 17917170
J Head Trauma Rehabil. 2006 Sep-Oct;21(5):375-8
pubmed: 16983222
J Sport Rehabil. 2019 Jan 1;28(1):99-105
pubmed: 28952910
Sports Health. 2012 Mar;4(2):147-54
pubmed: 23016082
Br J Sports Med. 2017 Jun;51(11):838-847
pubmed: 28446457
J Athl Train. 2011 Jan-Feb;46(1):76-84
pubmed: 21214354
Clin J Sport Med. 2019 Nov;29(6):494-499
pubmed: 31688181
JAMA Pediatr. 2019 Apr 1;173(4):319-325
pubmed: 30715132
PLoS One. 2013 Apr 09;8(4):e61483
pubmed: 23585901
J Neurotrauma. 2015 May 15;32(10):739-51
pubmed: 25144903
Phys Sportsmed. 2005 Apr;33(4):29-44
pubmed: 20086357
J Head Trauma Rehabil. 2013 Jul-Aug;28(4):250-9
pubmed: 22688215
Psychol Rep. 1967 Aug;21(1):70-2
pubmed: 6078391
J Athl Train. 2017 Mar;52(3):299-308
pubmed: 28387557