Individual-Molecule Perspective Analysis of Chemical Reaction Networks: The Case of a Light-Driven Supramolecular Pump.
molecular machines
nonequilibrium processes
reaction networks
self-assembly
systems chemistry
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
01 Oct 2019
01 Oct 2019
Historique:
received:
27
06
2019
pubmed:
6
8
2019
medline:
6
8
2019
entrez:
6
8
2019
Statut:
ppublish
Résumé
The first study in which stochastic simulations of a two-component molecular machine are performed in the mass-action regime is presented. This system is an autonomous molecular pump consisting of a photoactive axle that creates a directed flow of rings through it by exploiting light energy away from equilibrium. The investigation demonstrates that the pump can operate in two regimes, both experimentally accessible, in which light-driven steps can be rate-determining or not. The number of photons exploited by an individual molecular pump, as well as the precision of cycling and the overall efficiency, critically rely on the operating regime of the machine. This approach provides useful information not only to guide the chemical design of a self-assembling molecular device with desired features, but also to elucidate the effect of the environment on its performance, thus facilitating its experimental investigation.
Identifiants
pubmed: 31379048
doi: 10.1002/anie.201908026
pmc: PMC6899705
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
14341-14348Subventions
Organisme : H2020 European Research Council
ID : 692981
Organisme : H2020 European Research Council
ID : 681456
Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
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