Accuracy of Curable Sexually Transmitted Infections and Genital Mycoplasmas Screening by Multiplex Real-Time PCR Using a Self-Collected Veil among Adult Women in Sub-Saharan Africa.


Journal

Infectious diseases in obstetrics and gynecology
ISSN: 1098-0997
Titre abrégé: Infect Dis Obstet Gynecol
Pays: Egypt
ID NLM: 9318481

Informations de publication

Date de publication:
2019
Historique:
received: 27 02 2019
revised: 15 04 2019
accepted: 20 05 2019
entrez: 6 8 2019
pubmed: 6 8 2019
medline: 7 1 2020
Statut: epublish

Résumé

Sexually transmitted infections (STIs) are highly prevalent in sub-Saharan Africa. Genital self-sampling may facilitate the screening of STIs in hard-to-reach remote populations far from large health care centers and may increase screening rates. The cross-sectional Adult women living in N'Djamena, the capital city of Chad, were recruited from the community and referred to the clinic for women's sexual health " A total of 251 women (mean age, 35.1 years) were prospectively enrolled. Only seven (2.8%) women were found to be infected with at least one common STIs [ Veil-based self-collection of female genital secretions constitutes a convenient tool to collect in gentle way cervicovaginal secretions for accurate molecular detection of genital bacteria. Such sampling procedure could be easily implemented in STIs clinics in sub-Saharan Africa.

Sections du résumé

Background
Sexually transmitted infections (STIs) are highly prevalent in sub-Saharan Africa. Genital self-sampling may facilitate the screening of STIs in hard-to-reach remote populations far from large health care centers and may increase screening rates. The cross-sectional
Methods
Adult women living in N'Djamena, the capital city of Chad, were recruited from the community and referred to the clinic for women's sexual health "
Results
A total of 251 women (mean age, 35.1 years) were prospectively enrolled. Only seven (2.8%) women were found to be infected with at least one common STIs [
Conclusions
Veil-based self-collection of female genital secretions constitutes a convenient tool to collect in gentle way cervicovaginal secretions for accurate molecular detection of genital bacteria. Such sampling procedure could be easily implemented in STIs clinics in sub-Saharan Africa.

Identifiants

pubmed: 31379424
doi: 10.1155/2019/8639510
pmc: PMC6662439
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8639510

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Zita Aleyo Nodjikouambaye (ZA)

Service de Gynécologie-Obstétrique, Hôpital de la Mère et de l'Enfant, N'Djamena, Chad.
Ecole Doctorale Régionale en Infectiologie Tropicale de Franceville, Franceville, Gabon.

Fabrice Compain (F)

Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.
INSERM UMRS 1138, UPMC Université (Paris VI), Université Paris Descartes (Paris V) and Université Paris Diderot (Paris VII), Centre de Recherche Biomédicale des Cordeliers, Paris, France.
Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.

Damtheou Sadjoli (D)

Cabinet Médical de Gynécologie-Obstétrique "La Renaissance Plus", N'Djamena, Chad.

Ralph-Sydney Mboumba Bouassa (RS)

Ecole Doctorale Régionale en Infectiologie Tropicale de Franceville, Franceville, Gabon.
Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.

Hélène Péré (H)

Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.
INSERM UMRS 1138, UPMC Université (Paris VI), Université Paris Descartes (Paris V) and Université Paris Diderot (Paris VII), Centre de Recherche Biomédicale des Cordeliers, Paris, France.
Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.

David Veyer (D)

Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.

Leman Robin (L)

Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.

Chatté Adawaye (C)

Institut National Supérieur des Sciences et Techniques d'Abéché, Abéché, Chad.

Serge Tonen-Wolyec (S)

Ecole Doctorale Régionale en Infectiologie Tropicale de Franceville, Franceville, Gabon.
Faculté de Médecine, Université de Bunia, Bunia, Democratic Republic of the Congo.
Faculté de Médecine et de Pharmacie, Université de Kisangani, Kisangani, Democratic Republic of the Congo.

Ali Mahamat Moussa (AM)

Faculté de Médecine, N'Djamena, Chad.
Service de Gastro-Entérologie, Hôpital Général de Référence Nationale, N'Djamena, Chad.

Donato Koyalta (D)

UNAIDS, N'Djamena, Chad.

Laurent Belec (L)

Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, Paris, France.
INSERM UMRS 1138, UPMC Université (Paris VI), Université Paris Descartes (Paris V) and Université Paris Diderot (Paris VII), Centre de Recherche Biomédicale des Cordeliers, Paris, France.
Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.

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