Impact of Prehospital Mobile Intensive Care Unit Intervention on Mortality of Patients with Sepsis.

Mobile intensive care unit mortality prehospital setting sepsis

Journal

Turkish journal of anaesthesiology and reanimation
ISSN: 2667-677X
Titre abrégé: Turk J Anaesthesiol Reanim
Pays: Turkey
ID NLM: 101680817

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 26 07 2018
accepted: 18 09 2018
entrez: 6 8 2019
pubmed: 6 8 2019
medline: 6 8 2019
Statut: ppublish

Résumé

The outcome of sepsis relies on the early diagnosis and implementation of appropriate treatments. For management of out-of-hospital patients with sepsis, prehospital emergency services, named Service d'Aide Médicale d'Urgence (SAMU) in France, dispatch to the scene an emergency mobile team (EMT) or a mobile intensive care unit (MICU) based on the patient's severity. Therefore, patients are admitted to the emergency department (ED) or to the intensive care unit (ICU). The impact of MICU intervention on patient's prognosis remains unclear. The aim of the present study was to describe the impact of MICU intervention on mortality on day 28 (D28) of patients with sepsis. We performed a retrospective study on patients with sepsis managed by prehospital teams, MICU or EMT, before admission to the ED or ICU. The primary outcome was mortality on D28. The SAMU received 30,642 calls during the study period with 140 patients with suspected sepsis. The suspected origin of sepsis was mainly pulmonary for 78 (55%) patients. Thirteen (9%) patients died on D28, 12 in the ED and 1 in the ICU. Two patients were admitted to the hospital by a MICU. After adjusting for confounding factors, the relative risk of mortality on D28 for patients admitted to the hospital by a MICU was 0.40. We describe an association between MICU intervention and mortality on D28. MICU intervention for out-of-hospital patients with sepsis is associated with 60% reduced mortality on D28. Larger studies are needed to confirm the impact of the intervention of MICU on mortality of patients with sepsis.

Identifiants

pubmed: 31380515
doi: 10.5152/TJAR.2019.26576
pii: tard-47-4-334
pmc: PMC6645836
doi:

Types de publication

Journal Article

Langues

eng

Pagination

334-341

Déclaration de conflit d'intérêts

Conflict of Interest: The authors have no conflicts of interest to declare.

Références

Ann Fr Anesth Reanim. 2000 Nov;19(9):654-61
pubmed: 11244703
N Engl J Med. 2001 Nov 8;345(19):1368-77
pubmed: 11794169
Am J Respir Crit Care Med. 2003 Jul 15;168(2):165-72
pubmed: 12851245
Resuscitation. 2004 Oct;63(1):7-9
pubmed: 15451580
Chest. 1992 Jun;101(6):1481-3
pubmed: 1600757
Crit Care Med. 2006 Jan;34(1):15-21
pubmed: 16374151
Heart. 2006 Oct;92(10):1378-83
pubmed: 16914481
Crit Care. 2006;10(4):311
pubmed: 16941754
J Can Acad Child Adolesc Psychiatry. 2006 Aug;15(3):126-34
pubmed: 18392182
Pharmacoepidemiol Drug Saf. 2008 Dec;17(12):1202-17
pubmed: 18972454
Eur Heart J. 2010 Oct;31(20):2501-55
pubmed: 20802248
Am J Emerg Med. 2012 Jan;30(1):51-6
pubmed: 21030181
Multivariate Behav Res. 2011 May;46(3):399-424
pubmed: 21818162
Acad Emerg Med. 2011 Sep;18(9):934-40
pubmed: 21883637
Crit Care Med. 2013 May;41(5):1167-74
pubmed: 23442987
Crit Care Resusc. 2013 Sep;15(3):162-71
pubmed: 23944201
Emerg Med Australas. 2013 Oct;25(5):406-15
pubmed: 24099368
Eur J Emerg Med. 2014 Oct;21(5):330-5
pubmed: 24185258
N Engl J Med. 2014 May 1;370(18):1683-93
pubmed: 24635773
J Med Assoc Thai. 2014 Jan;97 Suppl 1:S69-76
pubmed: 24855845
Chest. 2014 Nov;146(5):1205-1213
pubmed: 25033349
J Emerg Med. 2015 Aug;49(2):147-51
pubmed: 25802163
BMJ Open. 2015 Apr 28;5(4):e006801
pubmed: 25922097
Am J Respir Crit Care Med. 2016 Feb 1;193(3):259-72
pubmed: 26414292
JAMA. 2016 Feb 23;315(8):762-74
pubmed: 26903335
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
Open Forum Infect Dis. 2016 Jan 21;3(1):ofw010
pubmed: 26925430
MMWR Morb Mortal Wkly Rep. 2016 Apr 08;65(13):342-5
pubmed: 27054476
BMJ Open. 2016 Aug 05;6(8):e011218
pubmed: 27496231
Crit Care Med. 2017 Mar;45(3):395-406
pubmed: 27941371
Crit Care Med. 2017 Jun;45(6):1011-1018
pubmed: 28426466
Scand J Trauma Resusc Emerg Med. 2017 May 12;25(1):51
pubmed: 28499459
N Engl J Med. 2017 Jun 8;376(23):2235-2244
pubmed: 28528569
Prehosp Emerg Care. 2018 Jan-Feb;22(1):84-90
pubmed: 28792256
Am J Emerg Med. 2018 May;36(5):820-824
pubmed: 29056391
Scand J Trauma Resusc Emerg Med. 2017 Nov 3;25(1):108
pubmed: 29100549
Am J Emerg Med. 2018 Jun;36(6):1022-1026
pubmed: 29426799

Auteurs

Romain Jouffroy (R)

Department of Anaesthesia and Intensive Care Unit, SAMU, Hôpital Necker, University Paris Descartes, Paris, France.

Anastasia Saade (A)

Department of Anaesthesia and Intensive Care Unit, SAMU, Hôpital Necker, University Paris Descartes, Paris, France.

Pascal Philippe (P)

Department of Anaesthesia and Intensive Care Unit, SAMU, Hôpital Necker, University Paris Descartes, Paris, France.

Pierre Carli (P)

Department of Anaesthesia and Intensive Care Unit, SAMU, Hôpital Necker, University Paris Descartes, Paris, France.

Benoit Vivien (B)

Department of Anaesthesia and Intensive Care Unit, SAMU, Hôpital Necker, University Paris Descartes, Paris, France.

Classifications MeSH