Twelve-year results of LINAC-based radiosurgery for vestibular schwannomas.
Zwölfjahresergebnisse der LINAC-basierten Radiochirurgie für Vestibularisschwannome.
Adult
Aged
Aged, 80 and over
Facial Nerve
/ radiation effects
Female
Follow-Up Studies
Hearing
/ radiation effects
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Grading
Neoplasm Recurrence, Local
/ pathology
Neuroma, Acoustic
/ diagnostic imaging
Radiation Injuries
/ etiology
Radiosurgery
/ instrumentation
Radiotherapy Dosage
Retrospective Studies
Trigeminal Nerve
/ radiation effects
Young Adult
Hearing preservation
Koos tumor grade
Late toxicity
Radiosurgery
Vestibular schwannomas
Journal
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
ISSN: 1439-099X
Titre abrégé: Strahlenther Onkol
Pays: Germany
ID NLM: 8603469
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
07
12
2018
accepted:
10
07
2019
pubmed:
7
8
2019
medline:
13
6
2020
entrez:
7
8
2019
Statut:
ppublish
Résumé
To report long-term outcomes of 53 patients with vestibular schwannomas (VS) submitted to a single high-dose LINAC-based radiosurgery (SRS) in our institution. 48 (92%) patients were evaluable for clinical and MRI response as well as late toxicity. At a median follow-up of 12 years (range 2-16 years), local control (LC), hearing capacity, trigeminal and facial nerve function, and toxicity were assessed. Hearing capacity was classified according to the Gardner-Robertson scale, where class I-II patients had "serviceable hearing." Median dose of SRS was 16.5 Gy (range 13-20 Gy) and median tumor volume 1.7 cm LC and hearing preservation after SRS were excellent. Toxicity proved acceptable. Although the median administered dose (16.5 Gy) was rather high, the only factor which significantly influenced late toxicity was Koos tumor grade III-IV.
Identifiants
pubmed: 31384957
doi: 10.1007/s00066-019-01498-7
pii: 10.1007/s00066-019-01498-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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