A serum protein signature of APOE genotypes in centenarians.


Journal

Aging cell
ISSN: 1474-9726
Titre abrégé: Aging Cell
Pays: England
ID NLM: 101130839

Informations de publication

Date de publication:
12 2019
Historique:
received: 14 02 2019
revised: 07 04 2019
accepted: 07 07 2019
pubmed: 7 8 2019
medline: 15 9 2020
entrez: 7 8 2019
Statut: ppublish

Résumé

The discovery of treatments to prevent or delay dementia and Alzheimer's disease is a priority. The gene APOE is associated with cognitive change and late-onset Alzheimer's disease, and epidemiological studies have provided strong evidence that the e

Identifiants

pubmed: 31385390
doi: 10.1111/acel.13023
pmc: PMC6826130
doi:

Substances chimiques

Apolipoproteins E 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13023

Subventions

Organisme : NIA NIH HHS
ID : R21 AG056630
Pays : United States
Organisme : NIA NIH HHS
ID : UH3 AG064704
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG061844
Pays : United States
Organisme : NIA NIH HHS
ID : UH2 AG064704
Pays : United States
Organisme : NIA NIH HHS
ID : U19 AG023122
Pays : United States

Informations de copyright

© 2019 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

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Auteurs

Paola Sebastiani (P)

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.

Stefano Monti (S)

Bioinformatics Program, Boston University, Boston, Massachusetts.
Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.

Melody Morris (M)

Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.

Anastasia Gurinovich (A)

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Bioinformatics Program, Boston University, Boston, Massachusetts.

Tanaka Toshiko (T)

Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland.

Stacy L Andersen (SL)

Geriatrics Section, Department of Medicine, School of Medicine and Boston Medical Center, Boston University, Boston, MA.

Benjamin Sweigart (B)

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.

Luigi Ferrucci (L)

Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland.

Lori L Jennings (LL)

Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.

David J Glass (DJ)

Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.

Thomas T Perls (TT)

Geriatrics Section, Department of Medicine, School of Medicine and Boston Medical Center, Boston University, Boston, MA.

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