Whole-genome sequencing for rapid, reliable and routine investigation of
Contact investigation
Mycobacterium tuberculosis
genotyping outbreak
molecular epidemiology
whole-genome sequencing
Journal
New microbes and new infections
ISSN: 2052-2975
Titre abrégé: New Microbes New Infect
Pays: England
ID NLM: 101624750
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
12
05
2019
revised:
11
06
2019
accepted:
24
06
2019
entrez:
8
8
2019
pubmed:
8
8
2019
medline:
8
8
2019
Statut:
epublish
Résumé
Contact investigations following the diagnosis of active tuberculosis (TB) are paramount for the control of the disease. Epidemiological data are very powerful for contact tracing but might be delayed and/or difficult to integrate, especially in the setting of multiple contact-tracing investigations. The aim of this study was to address the added-value of whole-genome sequencing (WGS) to routine local TB surveillance systems. From November 2016 to July 2017, the local TB surveillance system identified three clusters that could constitute a unique larger outbreak. Epidemiological and clinical information were integrated with WGS genotyping data of
Identifiants
pubmed: 31388433
doi: 10.1016/j.nmni.2019.100582
pii: S2052-2975(19)30079-4
pii: 100582
pmc: PMC6669808
doi:
Types de publication
Journal Article
Langues
eng
Pagination
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