Evaluation of the clinical and economic impact of delays to surgery in patients with periampullary cancer.


Journal

BJS open
ISSN: 2474-9842
Titre abrégé: BJS Open
Pays: England
ID NLM: 101722685

Informations de publication

Date de publication:
08 2019
Historique:
received: 13 11 2018
accepted: 22 02 2019
entrez: 8 8 2019
pubmed: 8 8 2019
medline: 8 8 2019
Statut: epublish

Résumé

Early treatment is the only potential cure for periampullary cancer. The pathway to surgery is complex and involves multiple procedures across local and specialist hospitals. The aim of this study was to analyse variability within this pathway, and its impact on cost and outcomes. Patients undergoing surgery for periampullary cancer (2011-2016) were identified retrospectively and their pathway to surgery was analysed. Patients who had early surgery (shortest quartile, Q1) were compared with those having late surgery (longest quartile, Q4). A total of 483 patients were included in the study, with 121 and 124 patients in Q1 and Q4 respectively. The median time from initial CT to surgery was 21 days for Q1 There is wide variation across the entire pathway, suggesting that multiple strategies are required to enable early surgery. Defining an effective pathway by anticipating the need for investigations and avoiding biliary drainage reduces unplanned admissions and costs and increases resection rates.

Sections du résumé

Background
Early treatment is the only potential cure for periampullary cancer. The pathway to surgery is complex and involves multiple procedures across local and specialist hospitals. The aim of this study was to analyse variability within this pathway, and its impact on cost and outcomes.
Methods
Patients undergoing surgery for periampullary cancer (2011-2016) were identified retrospectively and their pathway to surgery was analysed. Patients who had early surgery (shortest quartile, Q1) were compared with those having late surgery (longest quartile, Q4).
Results
A total of 483 patients were included in the study, with 121 and 124 patients in Q1 and Q4 respectively. The median time from initial CT to surgery was 21 days for Q1
Conclusion
There is wide variation across the entire pathway, suggesting that multiple strategies are required to enable early surgery. Defining an effective pathway by anticipating the need for investigations and avoiding biliary drainage reduces unplanned admissions and costs and increases resection rates.

Identifiants

pubmed: 31388640
doi: 10.1002/bjs5.50161
pii: BJS550161
pmc: PMC6677092
doi:

Types de publication

Journal Article

Langues

eng

Pagination

476-484

Subventions

Organisme : Pancreatic Cancer UK
ID : CPA2015_05_BIRMINGHAM
Pays : United Kingdom

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Auteurs

R Pandé (R)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

J Hodson (J)

Institute of Translational Medicine University Hospitals Birmingham NHS Foundation Trust Birmingham UK.

A Murray (A)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

F Marcon (F)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

M Kalisvaart (M)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

R Marudanayagam (R)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

R P Sutcliffe (RP)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

D F Mirza (DF)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

J Isaac (J)

Liver Unit Queen Elizabeth Hospital Birmingham UK.

K J Roberts (KJ)

Liver Unit Queen Elizabeth Hospital Birmingham UK.
Institute of Immunology and Immunotherapy University of Birmingham Birmingham UK.

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