The HOME Study: study protocol for a randomised controlled trial comparing the addition of Proactive Psychological Medicine to usual care, with usual care alone, on the time spent in hospital by older acute hospital inpatients.


Journal

Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253

Informations de publication

Date de publication:
07 Aug 2019
Historique:
received: 22 11 2018
accepted: 05 06 2019
entrez: 9 8 2019
pubmed: 9 8 2019
medline: 14 2 2020
Statut: epublish

Résumé

Prolonged acute hospital stays are a major problem for older people and for health services. Failure to effectively manage the psychological and social aspects of illness is an important cause of prolonged hospital stays. Proactive Psychological Medicine (PPM) is a new way of providing psychiatry services to medical wards. PPM is proactive, focussed, intensive and integrated with medical care. A major aim of PPM is to reduce the time older people spend in hospital because of unmanaged psychological and social problems. The HOME Study will test the effectiveness and cost-effectiveness of PPM. A two-arm parallel-group randomised controlled superiority trial, with a linked health economic analysis and an embedded process evaluation, will be conducted at three sites. A total of 3588 participants will be recruited and randomised to usual care or usual care plus PPM. The primary outcome is the number of days spent as an inpatient in a general hospital in the month (30 days) post-randomisation. Secondary outcomes for each participant (measured at 1 and 3 months) include quality of life, independent functioning, symptoms of anxiety and depression, cognitive function, and their experience of the hospital stay. The trial has been designed to produce findings that are generalisable to all older medical inpatients (including those with cognitive impairment). It will provide information on the effectiveness and cost-effectiveness of PPM, which we hope will be of value to patients, clinicians, managers and service planners. ISRCTN86120296 . Registered on 3 January 2018.

Sections du résumé

BACKGROUND BACKGROUND
Prolonged acute hospital stays are a major problem for older people and for health services. Failure to effectively manage the psychological and social aspects of illness is an important cause of prolonged hospital stays. Proactive Psychological Medicine (PPM) is a new way of providing psychiatry services to medical wards. PPM is proactive, focussed, intensive and integrated with medical care. A major aim of PPM is to reduce the time older people spend in hospital because of unmanaged psychological and social problems. The HOME Study will test the effectiveness and cost-effectiveness of PPM.
METHODS/DESIGN METHODS
A two-arm parallel-group randomised controlled superiority trial, with a linked health economic analysis and an embedded process evaluation, will be conducted at three sites. A total of 3588 participants will be recruited and randomised to usual care or usual care plus PPM. The primary outcome is the number of days spent as an inpatient in a general hospital in the month (30 days) post-randomisation. Secondary outcomes for each participant (measured at 1 and 3 months) include quality of life, independent functioning, symptoms of anxiety and depression, cognitive function, and their experience of the hospital stay.
DISCUSSION CONCLUSIONS
The trial has been designed to produce findings that are generalisable to all older medical inpatients (including those with cognitive impairment). It will provide information on the effectiveness and cost-effectiveness of PPM, which we hope will be of value to patients, clinicians, managers and service planners.
TRIAL REGISTRATION BACKGROUND
ISRCTN86120296 . Registered on 3 January 2018.

Identifiants

pubmed: 31391073
doi: 10.1186/s13063-019-3502-5
pii: 10.1186/s13063-019-3502-5
pmc: PMC6686488
doi:

Types de publication

Clinical Trial Protocol Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

483

Subventions

Organisme : Department of Health
ID : HS&DR/15/11/16
Pays : United Kingdom
Organisme : Health Services Research Programme
ID : 15/11/16

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Auteurs

Jane Walker (J)

Psychological Medicine Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK. jane.walker@psych.ox.ac.uk.

Katy Burke (K)

Psychological Medicine Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK.

Mark Toynbee (M)

Psychological Medicine Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK.

Maike van Niekerk (M)

Psychological Medicine Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK.

Chris Frost (C)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

Nicholas Magill (N)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

Simon Walker (S)

Centre for Health Economics, University of York, Heslington, York, UK.

Mark Sculpher (M)

Centre for Health Economics, University of York, Heslington, York, UK.

Ian R White (IR)

London Hub for Trials Methodology Research, MRC Clinical Trials Unit at UCL, London, UK.

Michael Sharpe (M)

Psychological Medicine Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK.

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