Outdoor air pollution and the burden of childhood asthma across Europe.
Journal
The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
21
11
2018
accepted:
07
07
2019
pubmed:
9
8
2019
medline:
8
10
2020
entrez:
9
8
2019
Statut:
epublish
Résumé
Emerging evidence suggests that air pollution may contribute to childhood asthma development. We estimated the burden of incident childhood asthma that may be attributable to outdoor nitrogen dioxide (NO We combined country-level childhood incidence rates and pooled exposure-response functions with childhood (age 1-14 years) population counts, and exposure estimates at 1 540 386 1 km×1 km cells, across 18 European countries and 63 442 419 children. Annual average pollutant concentrations were obtained from a validated and harmonised European land-use regression model. We investigated two exposure reduction scenarios. For the first, we used recommended annual World Health Organization (WHO) air quality guideline values. For the second, we used the minimum air pollution levels recorded across 41 studies in the underlying meta-analysis. NO A significant proportion of childhood asthma cases may be attributable to outdoor air pollution and these cases could be prevented. Our estimates underline an urgent need to reduce children's exposure to air pollution.
Sections du résumé
BACKGROUND
Emerging evidence suggests that air pollution may contribute to childhood asthma development. We estimated the burden of incident childhood asthma that may be attributable to outdoor nitrogen dioxide (NO
METHODS
We combined country-level childhood incidence rates and pooled exposure-response functions with childhood (age 1-14 years) population counts, and exposure estimates at 1 540 386 1 km×1 km cells, across 18 European countries and 63 442 419 children. Annual average pollutant concentrations were obtained from a validated and harmonised European land-use regression model. We investigated two exposure reduction scenarios. For the first, we used recommended annual World Health Organization (WHO) air quality guideline values. For the second, we used the minimum air pollution levels recorded across 41 studies in the underlying meta-analysis.
RESULTS
NO
CONCLUSIONS
A significant proportion of childhood asthma cases may be attributable to outdoor air pollution and these cases could be prevented. Our estimates underline an urgent need to reduce children's exposure to air pollution.
Identifiants
pubmed: 31391220
pii: 13993003.02194-2018
doi: 10.1183/13993003.02194-2018
pii:
doi:
Substances chimiques
Particulate Matter
0
Carbon
7440-44-0
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Meta-Analysis
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright ©ERS 2019.
Déclaration de conflit d'intérêts
Conflict of interest: H. Khreis has nothing to disclose. Conflict of interest: M. Cirach has nothing to disclose. Conflict of interest: N. Mueller has nothing to disclose. Conflict of interest: K. de Hoogh has nothing to disclose. Conflict of interest: G. Hoek has nothing to disclose. Conflict of interest: M.J. Nieuwenhuijsen has nothing to disclose. Conflict of interest: D. Rojas-Rueda has nothing to disclose.