Novel therapeutic targets for allergic airway disease in children.
allergic airway disease
allergic rhinitis
asthma
biologics
children
chronic rhinosinusitis
immunotherapy
Journal
Drugs in context
ISSN: 1745-1981
Titre abrégé: Drugs Context
Pays: England
ID NLM: 101262187
Informations de publication
Date de publication:
2019
2019
Historique:
received:
03
04
2019
revised:
30
05
2019
accepted:
03
06
2019
entrez:
9
8
2019
pubmed:
9
8
2019
medline:
9
8
2019
Statut:
epublish
Résumé
The aim of precision medicine is setting up targeted therapies for selected patients that would ideally have high effectiveness and few side effects. This is made possible by targeted therapy drugs that selectively act on a specific pathway. Precision medicine is spreading to many medical specialties, and there is increasing interest in the context of allergic airway diseases, such as allergic rhinitis, chronic rhinosinusitis, and asthma. This review is an update of new targets in the treatment of childhood allergic upper airway diseases and asthma, including the most recent biologic drugs that have already been licensed or are in the pipeline to be tested with children.
Identifiants
pubmed: 31391855
doi: 10.7573/dic.212590
pii: dic-8-212590
pmc: PMC6668505
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
212590Déclaration de conflit d'intérêts
Disclosure and potential conflicts of interest: The authors declare that they have no conflicts of interest. The International Committee of Medical Journal Editors (ICMJE) Potential Conflicts of Interests form for the authors is available for download at http://www.drugsincontext.com/wp-content/uploads/2019/06/dic.212590-COI.pdf
Références
J Allergy Clin Immunol. 1999 Sep;104(3 Pt 1):534-40
pubmed: 10482824
Thorax. 2000 Oct;55 Suppl 2:S26-7
pubmed: 10992552
Lancet. 2000 Dec 23-30;356(9248):2144-8
pubmed: 11191542
Respir Med. 2001 Jan;95(1):9-12
pubmed: 11207024
Pediatrics. 2001 Aug;108(2):E36
pubmed: 11483846
J Allergy Clin Immunol. 2001 Aug;108(2):184-90
pubmed: 11496232
Eur Respir J. 2001 Aug;18(2):254-61
pubmed: 11529281
JAMA. 2001 Dec 19;286(23):2956-67
pubmed: 11743836
J Allergy Clin Immunol. 2002 Feb;109(2):251-6
pubmed: 11842293
J Allergy Clin Immunol. 2002 Feb;109(2):274-80
pubmed: 11842297
Thorax. 2002 Jul;57(7):643-8
pubmed: 12096210
Lancet. 2002 Nov 30;360(9347):1715-21
pubmed: 12480423
Clin Exp Allergy. 2003 Feb;33(2):206-10
pubmed: 12580913
J Allergy Clin Immunol. 2004 Jan;113(1):86-93
pubmed: 14713912
Curr Opin Pulm Med. 2004 Jan;10(1):44-50
pubmed: 14749605
Blood. 2004 Nov 15;104(10):3086-90
pubmed: 15280196
Hum Hered. 2004;58(3-4):131-8
pubmed: 15812169
Am J Respir Crit Care Med. 2005 Aug 15;172(4):453-9
pubmed: 15901605
Allergy. 2006 Jan;61(1):3-14
pubmed: 16364151
Allergy. 2006 Jul;61(7):855-9
pubmed: 16792584
J Allergy Clin Immunol. 2006 Nov;118(5):1133-41
pubmed: 17088140
Respir Med. 2007 Jul;101(7):1483-92
pubmed: 17339107
Allergy Asthma Proc. 2007 Jan-Feb;28(1):40-3
pubmed: 17390756
Allergy Asthma Proc. 2007 Jan-Feb;28(1):74-8
pubmed: 17390762
Allergy. 2007 Aug;62(8):943-8
pubmed: 17620073
Pediatr Allergy Immunol. 2007 Nov;18 Suppl 18:10-2
pubmed: 17767599
Allergy. 2007 Dec;62(12):1379-86
pubmed: 17822449
BMJ. 2007 Sep 8;335(7618):502-7
pubmed: 17823191
Allergy. 2008 Mar;63(3):255-60
pubmed: 17944984
Chest. 2008 Mar;133(3):599-609
pubmed: 17951626
J Allergy Clin Immunol. 2008 Jan;121(1):257-8
pubmed: 18206513
Allergy. 2008 Apr;63 Suppl 86:8-160
pubmed: 18331513
Br J Pharmacol. 2008 Oct;155(3):288-90
pubmed: 18660832
Lancet. 2008 Sep 20;372(9643):1049-57
pubmed: 18805333
N Engl J Med. 1991 Oct 10;325(15):1067-71
pubmed: 1891008
J Allergy Clin Immunol. 2009 Feb;123(2):472-8
pubmed: 19064280
N Engl J Med. 2009 Mar 5;360(10):973-84
pubmed: 19264686
Clin Exp Allergy. 2009 Jun;39(6):788-97
pubmed: 19302249
Curr Opin Allergy Clin Immunol. 2010 Feb;10(1):1-7
pubmed: 20010094
Allergy Asthma Clin Immunol. 2006 Sep 15;2(3):117-23
pubmed: 20525156
Rhinology. 2010 Sep;48(3):318-24
pubmed: 21038023
Allergy. 2011 Jun;66(6):740-52
pubmed: 21443635
Respir Med. 2011 Nov;105(11):1611-21
pubmed: 21764573
J Allergy Clin Immunol. 2011 Nov;128(5):989-95.e1-8
pubmed: 21958585
Int J Immunopathol Pharmacol. 2011 Oct;24(4 Suppl):7-12
pubmed: 22032779
Nat Med. 2012 May 04;18(5):716-25
pubmed: 22561835
J Biol Regul Homeost Agents. 2012 Jan-Mar;26(1 Suppl):S77-83
pubmed: 22691254
Allergy Asthma Proc. 2012 May-Jun;33 Suppl 1:47-50
pubmed: 22794687
Lancet. 2012 Aug 18;380(9842):651-9
pubmed: 22901886
J Allergy Clin Immunol. 2013 Jan;131(1):110-6.e1
pubmed: 23021878
Int Arch Allergy Immunol. 2013;161(2):116-21
pubmed: 23343652
J Allergy Clin Immunol. 2013 Jun;131(6):1479-90
pubmed: 23587334
Eur Respir J. 2014 Feb;43(2):343-73
pubmed: 24337046
Int J Pediatr Otorhinolaryngol. 2014 Feb;78(2):343-7
pubmed: 24388318
Eur J Pediatr. 2014 Sep;173(9):1123-36
pubmed: 24809802
J Allergy Clin Immunol Pract. 2014 May-Jun;2(3):332-40.e1
pubmed: 24811026
Allergy. 2014 Jul;69(7):828-33
pubmed: 24815699
Clin Exp Allergy. 2014 Nov;44(11):1371-85
pubmed: 25200415
Expert Rev Clin Immunol. 2014 Oct;10(10):1337-47
pubmed: 25225773
Otolaryngol Head Neck Surg. 2014 Oct;151(4):542-53
pubmed: 25274375
Clin Exp Allergy. 2015 Jul;45(7):1170-88
pubmed: 25394891
Paediatr Drugs. 2014 Dec;16(6):491-502
pubmed: 25404353
Thorax. 2015 Feb;70(2):115-20
pubmed: 25422384
Int J Immunopathol Pharmacol. 2014 Oct-Dec;27(4):499-508
pubmed: 25572729
Expert Rev Respir Med. 2015 Apr;9(2):129-34
pubmed: 25578528
Sci Rep. 2015 Feb 03;5:8191
pubmed: 25645133
Allergy. 2015 Jun;70(6):674-81
pubmed: 25703927
J Otolaryngol Head Neck Surg. 2015 Mar 05;44:11
pubmed: 25890357
Expert Opin Drug Discov. 2015;10(9):1033-42
pubmed: 25979110
N Engl J Med. 2015 Jun 4;372(23):2229-34
pubmed: 26014593
PLoS One. 2015 Jul 02;10(7):e0131869
pubmed: 26135565
Pediatr Allergy Immunol. 2015 Dec;26(8):772-9
pubmed: 26266838
Expert Rev Clin Immunol. 2015;11(12):1321-33
pubmed: 26358006
Ann Allergy Asthma Immunol. 2015 Nov;115(5):335-40
pubmed: 26505931
Syst Rev. 2015 Nov 18;4:166
pubmed: 26581392
J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):38-46
pubmed: 26634586
J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):114-9
pubmed: 26634596
Expert Opin Emerg Drugs. 2016;21(1):57-67
pubmed: 26733401
Pediatr Pulmonol. 2016 Mar;51(3):316-28
pubmed: 26829581
J Allergy Clin Immunol. 2016 Feb;137(2):339-349.e10
pubmed: 26853126
Immunotherapy. 2016;8(3):331-49
pubmed: 26860435
World J Clin Pediatr. 2016 Feb 08;5(1):47-56
pubmed: 26862501
J Allergy Clin Immunol. 2016 May;137(5):1449-1456.e4
pubmed: 26949058
Respir Res. 2016 Mar 14;17:28
pubmed: 26975422
Respir Res. 2016 Mar 18;17:29
pubmed: 26993628
Pediatr Allergy Immunol. 2016 Aug;27(5):521-6
pubmed: 27062336
Pediatr Allergy Immunol. 2016 Aug;27(5):446-51
pubmed: 27090058
Lancet Respir Med. 2016 Jul;4(7):549-556
pubmed: 27177493
J Allergy Clin Immunol. 2016 Oct;138(4):1051-1059
pubmed: 27185571
J Allergy Clin Immunol. 2016 Nov;138(5):1344-1353
pubmed: 27544740
Expert Opin Biol Ther. 2017 Apr;17(4):429-434
pubmed: 28132528
Int Arch Allergy Immunol. 2017;172(2):99-105
pubmed: 28253520
Front Pediatr. 2017 Mar 03;5:44
pubmed: 28316969
J Allergy Clin Immunol. 2017 May;139(5):1431-1444
pubmed: 28477722
J Allergy Clin Immunol. 2017 Oct;140(4):950-958
pubmed: 28602936
J Investig Allergol Clin Immunol. 2017 Jun;27(Suppl. 1):1-35
pubmed: 28603089
J Allergy Clin Immunol. 2017 Oct;140(4):1024-1031.e14
pubmed: 28687232
J Asthma. 2018 Apr;55(4):385-390
pubmed: 28696802
Clin Transl Allergy. 2017 Aug 2;7:25
pubmed: 28775845
Allergy. 2018 Feb;73(2):470-478
pubmed: 28833265
Expert Rev Respir Med. 2017 Nov;11(11):855-865
pubmed: 28918658
Cochrane Database Syst Rev. 2017 Sep 21;9:CD010834
pubmed: 28933516
Expert Opin Drug Discov. 2018 Jan;13(1):51-63
pubmed: 29077521
Curr Respir Med Rev. 2017 Mar;13(1):36-42
pubmed: 29213221
BMJ Open. 2017 Dec 28;7(12):e016326
pubmed: 29288175
Curr Respir Med Rev. 2017 Mar;13(1):22-29
pubmed: 29290750
Ann Allergy Asthma Immunol. 2018 May;120(5):504-511.e4
pubmed: 29409951
Curr Med Res Opin. 2018 May;34(5):943-944
pubmed: 29421950
Eur Respir J. 2018 May 10;51(5):
pubmed: 29545284
Pediatrics. 2018 May;141(5):
pubmed: 29572287
Recent Pat Inflamm Allergy Drug Discov. 2018;12(2):103-109
pubmed: 29714140
N Engl J Med. 2018 Jun 28;378(26):2486-2496
pubmed: 29782217
N Engl J Med. 2018 Jun 28;378(26):2475-2485
pubmed: 29782224
Front Pediatr. 2018 Jun 19;6:170
pubmed: 29971223
Ann Allergy Asthma Immunol. 2018 Sep;121(3):293-305
pubmed: 30025907
Expert Rev Clin Immunol. 2018 Aug;14(8):657-663
pubmed: 30039714
Respir Med. 2018 Aug;141:94-99
pubmed: 30053979
Pediatr Allergy Immunol Pulmonol. 2018 Jun 1;31(2):44-55
pubmed: 30069422
Rev Alerg Mex. 2018 Jul-Sep;65(3):259-263
pubmed: 30176204
Front Pediatr. 2018 Aug 21;6:231
pubmed: 30186823
J Allergy Clin Immunol Pract. 2019 Feb;7(2):589-596.e3
pubmed: 30193936
Immunol Allergy Clin North Am. 2018 Nov;38(4):679-692
pubmed: 30342588
J Dermatolog Treat. 2018;29(sup4):10-11
pubmed: 30462557
Allergy Asthma Immunol Res. 2019 Jan;11(1):68-78
pubmed: 30479078
Allergy. 2019 May;74(5):999-1003
pubmed: 30481388
Allergy Asthma Proc. 2019 Jan 1;40(1):35-40
pubmed: 30582494
J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1636-1638
pubmed: 30772479
Front Immunol. 2019 Feb 04;10:74
pubmed: 30778348
J Asthma. 2019 Feb 22;:1-4
pubmed: 30795693
Am J Respir Crit Care Med. 1997 Jun;155(6):1828-34
pubmed: 9196082
J Clin Invest. 1997 Nov 15;100(10):2466-75
pubmed: 9366561