Hexachlorocyclohexane exposure alters the microbiome of colostrum in Chinese breastfeeding mothers.
Breast milk microbiota
Colostrum
Hexachlorocyclohexane
Microbiome
Pollution exposure
Journal
Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
20
04
2019
revised:
09
07
2019
accepted:
13
07
2019
pubmed:
9
8
2019
medline:
18
12
2019
entrez:
9
8
2019
Statut:
ppublish
Résumé
Breast milk, especially colostrum, is not just a source of nutrients and immune factors for the newborn, but also accumulates environmental persistent pollutants and its diverse microbes affect the early colonization of the newborn's gut. Little is known about associations between environmental pollutants and the microbial composition of human colostrum. We assessed the influence of hexachlorocyclohexane (HCH), a persistent organic pollutant (POP), in colostrums on the microbial composition of human colostrum samples. HCH concentrations in 89 colostrum samples collected from a population living on the easternmost island of China were measured via gas chromatography equipped with mass spectrometer (GC-MS), HCH exposure risks for infants via dietary intake of breast milk were assessed, and for 29 colostrum samples the microbiota were profiled using 16S rRNA gene pyrosequencing to assess the association with HCH exposure levels. Our study confirmed high colostrum exposure levels of total HCHs (12.19 ± 13.68 μg L
Identifiants
pubmed: 31394347
pii: S0269-7491(19)31860-3
doi: 10.1016/j.envpol.2019.07.068
pii:
doi:
Substances chimiques
Environmental Pollutants
0
RNA, Ribosomal, 16S
0
Hexachlorocyclohexane
59NEE7PCAB
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112900Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.