Prognostic Factors in Anti-glomerular Basement Membrane Disease: A Multicenter Study of 119 Patients.
Goodpasture's disease
anti-glomerular basement membrane disease
glomerulonephritis
mortality
outcome
vasculitis
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2019
2019
Historique:
received:
19
12
2018
accepted:
03
07
2019
entrez:
10
8
2019
pubmed:
10
8
2019
medline:
21
10
2020
Statut:
epublish
Résumé
We report the overall and renal outcome in a French nationwide multicenter cohort of 119 patients with anti-glomerular basement membrane (anti-GBM) disease. Sixty-four patients (54%) had an exclusive renal involvement, 7 (6%) an isolated alveolar hemorrhage and 48 (40%) a combined renal and pulmonary involvement. Initial renal replacement therapy (RRT) was required in 78% of patients; 82% received plasmapheresis, 82% cyclophosphamide, and 9% rituximab. ANCA positive (28%) patients were older (70 vs. 47 years,
Identifiants
pubmed: 31396214
doi: 10.3389/fimmu.2019.01665
pmc: PMC6662558
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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