A design for the photoelectrochemical detection of miRNA-221 based on a tungsten diselenide-cysteine-dopamine nanoprobe coupled with mismatched catalytic hairpin assembly target recycling with ultra-low background noise.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
27 Aug 2019
27 Aug 2019
Historique:
pubmed:
10
8
2019
medline:
13
9
2019
entrez:
10
8
2019
Statut:
ppublish
Résumé
A strategy for the photoelectrochemical detection of miRNA with ultra-low background noise was developed using tungsten diselenide-cysteine-dopamine (WSe2/Cys/DA) as a nanoprobe coupled with mismatched catalytic hairpin assembly target recycling. A superior detection limit of 3.3 aM toward miRNA-221 was achieved.
Substances chimiques
MIRN221 microRNA, human
0
MicroRNAs
0
Molecular Probes
0
Selenium
H6241UJ22B
Cysteine
K848JZ4886
Tungsten
V9306CXO6G
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM