Phosphorylation of BECLIN-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia.

Animals Autophagy Beclin-1 / genetics Fusion Proteins, bcr-abl / genetics Humans Imatinib Mesylate / pharmacology Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics Mice Phosphorylation

Journal

Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435

Informations de publication

Date de publication:
05 2020
Historique:
received: 18 01 2019
accepted: 07 08 2019
pubmed: 11 8 2019
medline: 28 4 2021
entrez: 11 8 2019
Statut: ppublish

Résumé

Autophagy is a genetically regulated process of adaptation to metabolic stress and was recently shown to be involved in the treatment response of chronic myeloid leukemia (CML). However,

Identifiants

DOI: 10.3324/haematol.2018.212027 PMID: 31399521 PMC: PMC7193473
pubmed: 31399521
pii: haematol.2018.212027
doi: 10.3324/haematol.2018.212027
pmc: PMC7193473
doi:

Substances chimiques

Beclin-1 0
Imatinib Mesylate 8A1O1M485B
Fusion Proteins, bcr-abl EC 2.7.10.2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1285-1293

Informations de copyright

Copyright© 2020 Ferrata Storti Foundation.

Références

Autophagy. 2009 Aug;5(6):890-1
pubmed: 19556860
Leukemia. 2007 Mar;21(3):494-504
pubmed: 17252012
Leukemia. 2015 Apr;29(4):858-68
pubmed: 25249015
Autophagy. 2016 Jun 2;12(6):936-48
pubmed: 27168493
Nature. 1999 Dec 9;402(6762):672-6
pubmed: 10604474
N Engl J Med. 2006 Jun 15;354(24):2531-41
pubmed: 16775234
Science. 2012 Nov 16;338(6109):956-9
pubmed: 23112296
Nat Cell Biol. 2009 Apr;11(4):385-96
pubmed: 19270696
Oncotarget. 2017 Apr 4;8(14):23213-23227
pubmed: 28390196
Curr Opin Cell Biol. 2010 Apr;22(2):140-9
pubmed: 20097051
APMIS. 2007 Dec;115(12):1344-9
pubmed: 18184403
Development. 2012 Jul;139(14):2523-34
pubmed: 22696294
Blood. 2003 Jul 15;102(2):646-51
pubmed: 12663439
Blood. 2003 Jun 15;101(12):4701-7
pubmed: 12576334
Autophagy. 2012 May 1;8(5):826-37
pubmed: 22617445
N Engl J Med. 2006 Dec 7;355(23):2408-17
pubmed: 17151364
J Biol Chem. 2012 Nov 2;287(45):37997-8005
pubmed: 22955283
Nat Rev Cancer. 2007 Jun;7(6):441-53
pubmed: 17522713
J Clin Invest. 2003 Dec;112(12):1809-20
pubmed: 14638851
J Natl Cancer Inst. 2018 May 1;110(5):467-478
pubmed: 29165716
Immunol Rev. 2015 Jan;263(1):106-23
pubmed: 25510274
Leukemia. 2016 Aug;30(8):1725-33
pubmed: 27046463
Autophagy. 2009 Jul;5(5):713-6
pubmed: 19372752
Blood. 2011 Aug 25;118(8):2035-43
pubmed: 21693757
Oncogene. 2011 Apr 21;30(16):1855-67
pubmed: 21151168
Elife. 2015 Feb 18;4:
pubmed: 25693418
Cell. 2015 Jan 15;160(1-2):145-60
pubmed: 25594178
Oncogene. 2002 Aug 29;21(38):5868-76
pubmed: 12185586
Nat Rev Cancer. 2005 Mar;5(3):172-83
pubmed: 15719031
Cell Death Dis. 2016 Sep 08;7(9):e2361
pubmed: 27607576
Nat Rev Cancer. 2007 May;7(5):345-56
pubmed: 17457302
Leukemia. 2012 Aug;26(8):1752-60
pubmed: 22395361
Hum Pathol. 2010 Jan;41(1):107-12
pubmed: 19762066
Cell. 2013 Sep 12;154(6):1269-84
pubmed: 24034250
J Clin Oncol. 2008 Jul 10;26(20):3358-63
pubmed: 18519952
Cell. 2010 Feb 5;140(3):313-26
pubmed: 20144757
Cell Death Differ. 2011 Apr;18(4):571-80
pubmed: 21311563
J Clin Invest. 2008 Sep;118(9):3038-50
pubmed: 18704194
Autophagy. 2010 Apr;6(3):322-9
pubmed: 20224296
EBioMedicine. 2015 Mar;2(3):255-263
pubmed: 25825707
Autophagy. 2008 Nov;4(8):1067-8
pubmed: 18776739
Cell Mol Life Sci. 2016 Mar;73(5):985-1001
pubmed: 26658914
Lancet Oncol. 2010 Nov;11(11):1029-35
pubmed: 20965785
Leuk Res. 2010 Oct;34(10):1255-68
pubmed: 20537386
Cell. 2011 Sep 30;147(1):223-34
pubmed: 21962518
Int J Hematol. 2017 Mar;105(3):335-340
pubmed: 27848186
Mol Biosyst. 2014 Oct;10(10):2626-42
pubmed: 25057855
J Exp Med. 2009 Aug 31;206(9):1957-70
pubmed: 19687226
Pharmacol Res. 2016 Mar;105:164-75
pubmed: 26826398
PLoS Genet. 2014 Oct 02;10(10):e1004626
pubmed: 25275521
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15077-82
pubmed: 14657337
J Clin Invest. 2009 May;119(5):1109-23
pubmed: 19363292
Nat Cell Biol. 2009 Apr;11(4):468-76
pubmed: 19270693
Genes Dev. 2012 May 1;26(9):877-90
pubmed: 22549953
Blood. 2012 Oct 25;120(17):3555-62
pubmed: 22898604
Clin Cancer Res. 2003 Apr;9(4):1248-52
pubmed: 12684391
Curr Pathobiol Rep. 2013 Dec 1;1(4):231-238
pubmed: 24729948
Blood. 2011 Aug 25;118(8):2200-10
pubmed: 21715303
Leukemia. 2017 Nov;31(11):2376-2387
pubmed: 28366933
Blood. 2011 Sep 8;118(10):2840-8
pubmed: 21715304

Auteurs

Chuanjiang Yu (C)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Sivahari P Gorantla (SP)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Alina Müller-Rudorf (A)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Tony A Müller (TA)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Stefanie Kreutmair (S)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Corinna Albers (C)

Department of Medicine, Klinikum rechts der Isar, Technical University München, München, Germany.

Lena Jakob (L)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Lena J Lippert (LJ)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Zhenyu Yue (Z)

Department of Neurology and Neuroscience, Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY, USA.

Monika Engelhardt (M)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Marie Follo (M)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Robert Zeiser (R)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Tobias B Huber (TB)

Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
BIOSS Center for Biological Signalling Studies and Center for Systems Biology (ZBSA), Albert-Ludwigs-University, Freiburg, Germany.

Justus Duyster (J)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Anna L Illert (AL)

Department of Internal Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany lena.illert@uniklinik-freiburg.de.
German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines régulatrices de l'apoptose › Bécline-1 › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › Protéines proto-oncogènes c-bcr › Protéines de fusion bcr-abl › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Mésilate d'imatinib › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Leucémie myéloïde chronique BCR-ABL positive › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Phosphorylation of BECLIN-1 by BCR-ABL...
questionsmedicales.fr › Métabolisme › Phosphorylation › Phosphorylation of BECLIN-1 by BCR-ABL...