Vaccine Evolution and Its Application to Fight Modern Threats.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2019
Historique:
received: 08 05 2019
accepted: 09 07 2019
entrez: 13 8 2019
pubmed: 14 8 2019
medline: 21 10 2020
Statut: epublish

Résumé

Before the development of the first vaccine, infectious diseases were a major cause of death around the globe with life expectancy estimated to be <50 years. Three measures have helped to drastically reduce the burden of infectious diseases but only vaccines have proven to be able to eradicate infectious agents. Herein, we describe new methodologies that have paved the way for what is currently known as modern vaccinology and the use of vaccines to tackle antimicrobial resistance, the biggest global threat of our time.

Identifiants

pubmed: 31404139
doi: 10.3389/fimmu.2019.01722
pmc: PMC6669413
doi:

Substances chimiques

AIDS Vaccines 0
Antibodies, Monoclonal 0
Antibodies, Neutralizing 0
Antigens 0
Respiratory Syncytial Virus Vaccines 0
Vaccines 0

Types de publication

Historical Article Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1722

Subventions

Organisme : European Research Council
Pays : International

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Auteurs

Emanuele Andreano (E)

Department of Life Sciences, University of Siena, Siena, Italy.
GlaxoSmithKline, Siena, Italy.
vAMRes Lab, Toscana Life Sciences, Siena, Italy.

Ugo D'Oro (U)

GlaxoSmithKline, Siena, Italy.

Rino Rappuoli (R)

GlaxoSmithKline, Siena, Italy.
vAMRes Lab, Toscana Life Sciences, Siena, Italy.
Faculty of Medicine, Imperial College, London, United Kingdom.

Oretta Finco (O)

GlaxoSmithKline, Siena, Italy.

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Classifications MeSH