Comparison of supplemental oxygen delivery by continuous versus demand based flow systems in hypoxemic COPD patients - A randomized, single-blinded cross-over study.


Journal

Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438

Informations de publication

Date de publication:
09 2019
Historique:
received: 13 05 2019
revised: 02 08 2019
accepted: 05 08 2019
pubmed: 14 8 2019
medline: 25 8 2020
entrez: 13 8 2019
Statut: ppublish

Résumé

Supplemental oxygen is a recommended therapy option in stable hypoxemic COPD patients. Often, supplemental oxygen is provided by continuous flow (CF). However, demand oxygen delivery systems (DODS) that provide an oxygen bolus only during inspiration have gained increasing use as they prolong oxygen cylinder life (beside battery life). However, there is a lack of evidence if different DODS and CF devices are equivalent. Seventy hypoxemic COPD patients (FEV SpO Oxygen supplementation via DODS (based on liquid oxygen or as a concentrator) yielded comparable physiological effects during standardized walking in stable hypoxemic COPD patients like CF. However, 20% of patients showed a clinically relevant lower oxygen saturation while using a DODS device. Therefore, we suggest individual testing of oxygen saturation of DODS suitability.

Sections du résumé

BACKGROUND
Supplemental oxygen is a recommended therapy option in stable hypoxemic COPD patients. Often, supplemental oxygen is provided by continuous flow (CF). However, demand oxygen delivery systems (DODS) that provide an oxygen bolus only during inspiration have gained increasing use as they prolong oxygen cylinder life (beside battery life). However, there is a lack of evidence if different DODS and CF devices are equivalent.
METHODS
Seventy hypoxemic COPD patients (FEV
RESULTS
SpO
CONCLUSION
Oxygen supplementation via DODS (based on liquid oxygen or as a concentrator) yielded comparable physiological effects during standardized walking in stable hypoxemic COPD patients like CF. However, 20% of patients showed a clinically relevant lower oxygen saturation while using a DODS device. Therefore, we suggest individual testing of oxygen saturation of DODS suitability.

Identifiants

pubmed: 31404750
pii: S0954-6111(19)30258-6
doi: 10.1016/j.rmed.2019.08.001
pii:
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

26-32

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Rainer Gloeckl (R)

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Prevention, Rehabilitation and Sports Medicine, Technical University of Munich, Munich, Germany. Electronic address: rgloeckl@schoen-klinik.de.

Inga Jarosch (I)

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany.

Tessa Schneeberger (T)

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Pulmonary Rehabilitation, Philipps-University of Marburg, German Center for Lung Research (DZL), Marburg, Germany.

Claudia Fiedler (C)

Department of Prevention, Rehabilitation and Sports Medicine, Technical University of Munich, Munich, Germany.

Melody Lausen (M)

Department of Internal Medicine, Philipps University of Marburg, Marburg, Germany.

Julian Weingaertner (J)

Department of Internal Medicine, Philipps University of Marburg, Marburg, Germany.

Wolfgang Hitzl (W)

Research Office (Biostatistics), Paracelsus Medical University, Salzburg, Austria; Department of Ophthalmology and Optometry, Paracelsus Medical University, Salzburg, Austria; Research Program Experimental Ophthalmology and Glaucoma Research, Paracelsus Medical University, Salzburg, Austria.

Klaus Kenn (K)

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Pulmonary Rehabilitation, Philipps-University of Marburg, German Center for Lung Research (DZL), Marburg, Germany.

Andreas Rembert Koczulla (AR)

Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Pulmonary Rehabilitation, Philipps-University of Marburg, German Center for Lung Research (DZL), Marburg, Germany.

Articles similaires

Humans Robotic Surgical Procedures Male Female Aged
Humans Hernias, Diaphragmatic, Congenital Case-Control Studies Prospective Studies Sweden

UK Foot and Ankle Thromboembolism (UK-FATE).

Jitendra Mangwani, Linzy Houchen-Wolloff, Karan Malhotra et al.
1.00
Humans Venous Thromboembolism Male Female United Kingdom

Classifications MeSH