Clinical emergency care research in low-income and middle-income countries: opportunities and challenges.
diseases
disorders
injuries
public health
study design
Journal
BMJ global health
ISSN: 2059-7908
Titre abrégé: BMJ Glob Health
Pays: England
ID NLM: 101685275
Informations de publication
Date de publication:
2019
2019
Historique:
received:
08
11
2018
revised:
05
01
2019
accepted:
12
01
2019
entrez:
14
8
2019
pubmed:
14
8
2019
medline:
14
8
2019
Statut:
epublish
Résumé
Disease processes that frequently require emergency care constitute approximately 50% of the total disease burden in low-income and middle-income countries (LMICs). Many LMICs continue to deal with emergencies caused by communicable disease states such as pneumonia, diarrhoea, malaria and meningitis, while also experiencing a marked increase in non-communicable diseases, such as cardiovascular diseases, diabetes mellitus and trauma. For many of these states, emergency care interventions have been developed through research in high-income countries (HICs) and advances in care have been achieved. However, in LMICs, clinical research, especially interventional trials, in emergency care are rare. Furthermore, there exists minimal research on the emergency management of diseases, which are rarely encountered in HICs but impact the majority of LMIC populations. This paper explores challenges in conducting clinical research in patients with emergency conditions in LMICs, identifies examples of successful clinical research and highlights the system, individual and study design characteristics that made such research possible in LMICs. Derived from the available literature, a focused list of high impact research considerations are put forth.
Identifiants
pubmed: 31406600
doi: 10.1136/bmjgh-2018-001289
pii: bmjgh-2018-001289
pmc: PMC6666826
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e001289Commentaires et corrections
Type : ErratumIn
Déclaration de conflit d'intérêts
Competing interests: None declared.
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