Evaluation of nationwide referral pathways, investigation and treatment of suspected cauda equina syndrome in the United Kingdom.


Journal

British journal of neurosurgery
ISSN: 1360-046X
Titre abrégé: Br J Neurosurg
Pays: England
ID NLM: 8800054

Informations de publication

Date de publication:
2019
Historique:
pubmed: 14 8 2019
medline: 24 12 2019
entrez: 14 8 2019
Statut: ppublish

Résumé

Cauda equina syndrome (CES) is a spinal emergency with clinical symptoms and signs that have low diagnostic accuracy. National guidelines in the United Kingdom (UK) state that all patients should undergo an MRI prior to referral to specialist spinal units and surgery should be performed at the earliest opportunity. We aimed to evaluate the current practice of investigating and treating suspected CES in the UK. A retrospective, multicentre observational study of the investigation and management of patients with suspected CES was conducted across the UK, including all patients referred to a spinal unit over 6 months between 1st October 2016 and 31st March 2017. A total of 28 UK spinal units submitted data on 4441 referrals. Over half of referrals were made without any previous imaging (n = 2572, 57.9%). Of all referrals, 695 underwent surgical decompression (15.6%). The majority of referrals were made out-of-hours (n = 2229/3517, 63.4%). Patient location and pre-referral imaging were not associated with time intervals from symptom onset or presentation to decompression. Patients investigated outside of the spinal unit experienced longer time intervals from referral to undergoing the MRI scan. This is the largest known study of the investigation and management of suspected CES. We found that the majority of referrals were made without adequate investigations. Most patients were referred out-of-hours and many were transferred for an MRI without subsequently requiring surgery. Adherence to guidelines would reduce the number of referrals to spinal services by 72% and reduce the number of patient transfers by 79%.

Identifiants

pubmed: 31407596
doi: 10.1080/02688697.2019.1648757
doi:

Types de publication

Journal Article Multicenter Study Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-11

Investigateurs

Mohamed Abdelsadg (M)
Daniel P Brown (DP)
Alexandru Budu (A)
Aswin Chari (A)
Yasir Chowdhury (Y)
Gareth M Dobson (GM)
Venetia Giannakaki (V)
Shumaila Hasan (S)
Paul Hegarty (P)
Amad Khan (A)
Ursalan Khan (U)
Joseph Merola (J)
Kevin Owusu-Agyemang (K)
Fahid T Rasul (FT)
Asim Sheikh (A)
Kathrin J Whitehouse (KJ)
Mubariz B Ahmad (MB)
Thineskrishna Anbarasan (T)
Charlotte N Auty (CN)
Abigail Chan (A)
Ahmed Chowdhury (A)
Raquel Clark Castillo (RC)
John H Cousins (JH)
Nedal Dabab (N)
Agampodi Umanda N De Thabrew (AUN)
Christopher Derham (C)
Rui Duarte Armindo (R)
Navin Furtado (N)
Sujit Gnanakumar (S)
Jack Goody (J)
Binay Gurung (B)
Ting Hin Richard Ip (TH)
Zain Iqbal (Z)
Ali Am Jan (AA)
Hamzah A Khan (HA)
Chan Hee Koh (CH)
John E Lawrence (JE)
Jing Xian Lee (JX)
Aaron Loh (A)
Christopher Tj Madden-McKee (CT)
Lauren D McDonagh (LD)
Stephen McKeever (S)
Molly Nielsen (M)
Sarah E O'Beirne (SE)
Olivia Me Padfield (OM)
Sarah O Potts (SO)
Sebastian Povlsen (S)
Savva Pronin (S)
Ailidh S Ramsay (AS)
Thomas J Robb (TJ)
Amar Saxena (A)
Philippa L Serebriakoff (PL)
Sadaf Sohrabi (S)
Robert Spencer (R)
Steven Stewart (S)
John G Strain (JG)
Sarah Sturrock (S)
Matthew Yk Tang (MY)
Christos M Tolias (CM)
Nikolaos G Tzerakis (NG)
Ella G Wilkinson (EG)
Eunice Xing (E)
Ibrahim H Yasin (IH)

Auteurs

Daniel M Fountain (DM)

Division of Neurosurgery, Department of Clinical Neurosciences, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Simon C L Davies (SCL)

Department of Neurosurgery, Barts Health NHS Trust, London, UK.

Julie Woodfield (J)

Department of Clinical Neurosciences, NHS Lothian, Edinburgh, UK.
Department of Clinical Neuroscience, Western General Hospital, Edinburgh, UK.

Mohammed Kamel (M)

Department of Neurosurgery, Nottingham University Hospitals Foundation Trust, Nottingham, UK.

Paulina Majewska (P)

Department of Neurosurgery, Queen's Hospital, Romford, UK.

Ellie Edlmann (E)

Division of Neurosurgery, Department of Clinical Neurosciences, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Aimun A B Jamjoom (AAB)

Department of Clinical Neuroscience, Western General Hospital, Edinburgh, UK.

Ingrid Hoeritzauer (I)

Department of Clinical Neuroscience, Western General Hospital, Edinburgh, UK.
Centre for Clinical Brain Sciences, University of Edinburgh, UK.

Mueez Waqar (M)

Division of Academic Neurosurgery, Manchester, UK.

Dominic E Mahoney (DE)

Bristol Medical School, University of Bristol, Bristol, UK.

Dillon Vyas (D)

School of Medicine, University of Leeds, Leeds, UK.

Moritz W J Schramm (MWJ)

Department of Neurosurgery, Leeds General Infirmary, Leeds, UK.

Georgios Solomou (G)

Keele Medical School, Keele University, Keele, UK.

Francesca E C Dawkes (FEC)

Leicester Medical School, University of Leicester, Leicester, UK.

Heidi K Grant (HK)

Brighton and Sussex Medical School, Brighton, UK.

Jonathan E Attwood (JE)

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.

Alexandros Boukas (A)

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.

Dominic J Ballard (DJ)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, UK.

Emma Toman (E)

Department of Neurosurgery, Queen Elizabeth Hospital Birmingham, Birmingham, UK.

Matthew I Sanders (MI)

Department of Neurosurgery, Sheffield Teaching Hospitals, Sheffield, UK.

Beverly Cheserem (B)

Department of Neurosurgery, Brighton and Sussex University Hospital, Brighton, UK.

Saurabh Sinha (S)

Department of Neurosurgery, Sheffield Teaching Hospitals, Sheffield, UK.

Patrick Statham (P)

Department of Clinical Neuroscience, Western General Hospital, Edinburgh, UK.

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