Neurocritical care monitoring of encephalopathic children with acute liver failure: A systematic review.


Journal

Pediatric transplantation
ISSN: 1399-3046
Titre abrégé: Pediatr Transplant
Pays: Denmark
ID NLM: 9802574

Informations de publication

Date de publication:
11 2019
Historique:
received: 04 03 2019
revised: 14 06 2019
accepted: 04 07 2019
pubmed: 14 8 2019
medline: 26 8 2020
entrez: 14 8 2019
Statut: ppublish

Résumé

Research on non-invasive neuromonitoring specific to PALF is limited. This systematic review identifies and synthesis the existing literature on non-invasive approaches to monitoring for neurological sequelae in patients with PALF. A series of literature searches were performed to identify all publications pertaining to five different non-invasive neuromonitoring modalities, in line with PRISMA guidelines. Each modality was selected on the basis of its potential for direct or indirect measurement of cerebral perfusion; studies on electroencephalographic monitoring were therefore not sought. Data were recorded on study design, patient population, comparator groups, and outcomes. A preponderance of observational studies was observed, most with a small sample size. Few incorporated direct comparisons of different modalities; in particular, comparison to invasive intracranial pressure monitoring was largely lacking. The integration of current evidence is considered in the context of the clinically significant distinctions between pediatric and adult ALF, as well as the implications for planning of future investigations to best support the evidence-based clinical care of these patients.

Identifiants

pubmed: 31407855
doi: 10.1111/petr.13556
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13556

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Références

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Auteurs

Adam Hunt (A)

University College Hospital, London, UK.

Robert C Tasker (RC)

Harvard Medical School, Chair in Neurocritical Care, Boston Children's Hospital, Boston, MA.

Akash Deep (A)

Paediatric Intensive Care, King's College Hospital, London, UK.

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