Mechanisms of Leukemia Evolution: Lessons from a Congenital Syndrome.

Cell Transformation, Neoplastic Child Down Syndrome Humans Leukemia, Myeloid, Acute Myelodysplastic Syndromes Preleukemia

Journal

Cancer cell
ISSN: 1878-3686
Titre abrégé: Cancer Cell
Pays: United States
ID NLM: 101130617

Informations de publication

Date de publication:
12 08 2019
Historique:
entrez: 14 8 2019
pubmed: 14 8 2019
medline: 15 4 2020
Statut: ppublish

Résumé

Studies of the mechanisms of acute leukemia transformation from a preleukemic state in humans are hampered by the absence of clinical preleukemia syndromes. In this issue of Cancer Cell, Labuhn et al. provide a functional genomics view on the leukemic evolution from congenital preleukemia in children with Down syndrome.

Identifiants

DOI: 10.1016/j.ccell.2019.07.004 PMID: 31408616
pubmed: 31408616
pii: S1535-6108(19)30331-9
doi: 10.1016/j.ccell.2019.07.004
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

115-117

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Yehudit Birger (Y)

Division of Pediatric Hematology and Oncology, Schneider Children's Medical Center of Israel, Petach Tikva 49100, Israel.

Ruth Shiloh (R)

Division of Pediatric Hematology and Oncology, Schneider Children's Medical Center of Israel, Petach Tikva 49100, Israel.

Shai Izraeli (S)

Division of Pediatric Hematology and Oncology, Schneider Children's Medical Center of Israel, Petach Tikva 49100, Israel; Sackler Medical School, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel. Electronic address: sizraeli@gmail.com.

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Classifications MeSH

questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Transformation cellulaire néoplasique › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Maladies chromosomiques › Syndrome de Down › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Leucémies › Leucémie myéloïde › Leucémie aigüe myéloïde › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Maladies de la moelle osseuse › Syndromes myélodysplasiques › Mechanisms of Leukemia Evolution: Lessons from...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Préleucémie › Mechanisms of Leukemia Evolution: Lessons from...