Ethanol Extracts of Dietary Herb,
Alpinia
/ chemistry
Antineoplastic Agents
/ pharmacology
Breast Neoplasms
/ drug therapy
Cell Line, Tumor
Cell Movement
/ drug effects
Cell Proliferation
/ drug effects
Epidermal Growth Factor
/ metabolism
ErbB Receptors
/ metabolism
Ethanol
/ chemistry
Female
Humans
MAP Kinase Signaling System
/ drug effects
MCF-7 Cells
Phosphatidylinositol 3-Kinases
/ metabolism
Phosphorylation
/ drug effects
Plant Extracts
/ pharmacology
Proto-Oncogene Proteins c-akt
/ metabolism
Signal Transduction
/ drug effects
None
EGFR
PI3K/AKT
Ras-ERK
breast cancer
metastasis
Journal
Integrative cancer therapies
ISSN: 1552-695X
Titre abrégé: Integr Cancer Ther
Pays: United States
ID NLM: 101128834
Informations de publication
Date de publication:
Historique:
entrez:
15
8
2019
pubmed:
15
8
2019
medline:
24
1
2020
Statut:
ppublish
Résumé
Recent advances in mammography screening, chemotherapy, and adjuvant treatment modalities have improved the survival rate of women with breast cancer. Nevertheless, the breast tumor with metastatic progression is still life-threatening. Indeed, combination therapy with Ras-ERK and PI3K inhibitors is clinically effective in malignant breast cancer treatment. Constituents from genus
Identifiants
pubmed: 31409145
doi: 10.1177/1534735419866924
pmc: PMC6696839
doi:
Substances chimiques
Antineoplastic Agents
0
Plant Extracts
0
Ethanol
3K9958V90M
Epidermal Growth Factor
62229-50-9
ErbB Receptors
EC 2.7.10.1
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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