[Histiocytosis in the dermatological context of the new classification].
Histiozytäre Neoplasien im Kontext der aktuellen Klassifikation.
Erdheim Chester disease
Histiocytosis
Langerhans cell histiocytosis
Therapy outcome
Xanthogranuloma
Journal
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
ISSN: 1432-1173
Titre abrégé: Hautarzt
Pays: Germany
ID NLM: 0372755
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
pubmed:
16
8
2019
medline:
8
10
2019
entrez:
16
8
2019
Statut:
ppublish
Résumé
Histiocytoses comprises a heterogeneous group of inflammatory diseases for which dendritic cells and macrophages are the main cellular components. The inflammatory infiltrate can affect the skin and other organs, and clinical outcome varies from mild to lethal depending on the involved cell subset and organ infiltration as well as comorbidities. Until recently, the group of histiocytosis was divided into Langerhans cell histiocytosis, non-Langerhans cell histiocytosis and malignant histiocytosis. With the new classification from JF Emile et al., the subgroups were determined regarding clinical, histiopathological, radiological, phenotype, genetic, and molecular features. In this review, we explain the revised classification with emphasis on dermatological and molecular aspects.
Identifiants
pubmed: 31414152
doi: 10.1007/s00105-019-4460-2
pii: 10.1007/s00105-019-4460-2
doi:
Types de publication
Journal Article
Review
Langues
ger
Sous-ensembles de citation
IM
Pagination
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