Photoreceptor inputs to pupil control.


Journal

Journal of vision
ISSN: 1534-7362
Titre abrégé: J Vis
Pays: United States
ID NLM: 101147197

Informations de publication

Date de publication:
01 08 2019
Historique:
entrez: 16 8 2019
pubmed: 16 8 2019
medline: 31 1 2020
Statut: ppublish

Résumé

The size of the pupil depends on light level. Watson and Yellott (2012) developed a unified formula to predict pupil size from luminance, field diameter, age, and number of eyes. Luminance reflects input from the L and M cones in the retina but ignores the contribution of intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin, which are known to control the size of the pupil. We discuss the role of melanopsin in controlling pupil size by reanalyzing an extant data set (Bouma, 1962). We confirm that melanopsin-weighted quantities, in conjunction with Watson and Yellott's formula, adequately model intensity-dependent pupil size. We discuss the contributions of other photoreceptors into pupil control.

Identifiants

pubmed: 31415056
pii: 2748647
doi: 10.1167/19.9.5
pmc: PMC6699792
doi:

Substances chimiques

Rod Opsins 0
melanopsin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 204686/Z/16/Z
Pays : United Kingdom

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Auteurs

Manuel Spitschan (M)

Department of Experimental Psychology, University of Oxford, Oxford, UK.
Centre for Chronobiology, Psychiatric Hospital of the University of Basel (UPK), Basel, Switzerland.
Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, Basel, Switzerland.

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Classifications MeSH