Maternal serum concentrations of perfluoroalkyl substances during pregnancy and gestational weight gain: The Avon Longitudinal Study of Parents and Children.

Adult Alkanesulfonic Acids / blood Biological Monitoring Caprylates / blood Environmental Pollutants / blood Fatty Acids Female Fluorocarbons / blood Gestational Weight Gain Humans Infant, Newborn Male Pregnancy
ALSPAC Endocrine disruptors Gestational weight gain Perfluoroalkyl substances Perfluorohexane sulfonic acid (PFHxS) Perfluorononanoic acid (PFNA) Perfluorooctane sulfonic acid (PFOS) Perfluorooctanoic acid (PFOA)

Journal

Reproductive toxicology (Elmsford, N.Y.)
ISSN: 1873-1708
Titre abrégé: Reprod Toxicol
Pays: United States
ID NLM: 8803591

Informations de publication

Date de publication:
12 2019
Historique:
received: 09 04 2019
revised: 23 07 2019
accepted: 02 08 2019
pubmed: 16 8 2019
medline: 19 8 2020
entrez: 16 8 2019
Statut: ppublish

Résumé

Perfluoroalkyl substances (PFAS) are chemicals used in the manufacture of consumer products. PFAS may act as endocrine disruptors, influencing metabolic pathways and weight-related outcomes. Previous studies observed an association between perfluorooctane sulfonic acid (PFOS) and higher gestational weight gain among under-/normal weight mothers. We analyzed associations of maternal serum pregnancy concentrations of PFAS with gestational weight gain (GWG) using data from 905 women in a subsample of the Avon Longitudinal Study of Parents and Children. Women were routinely weighed in antenatal check-ups; absolute GWG was determined by subtracting the first weight measurement from the last. Linear regression was used to explore associations of maternal PFAS concentrations with absolute GWG, stratified by prepregnancy body mass index. Associations of maternal PFOS, perfluorooctanoic acid (PFOA), and perfluorohexane sulfonic acid (PFHxS) concentrations with absolute GWG were null; 10% higher PFOS was associated with GWG of -0.03 kg (95% CI: -0.11, 0.06) among under-/normal weight mothers. Ten percent higher perfluorononanoic acid (PFNA) was associated with a higher GWG of 0.09 kg (95% CI: 0.02, 0.16) among under-/normal weight mothers. Overall, findings suggest no association between maternal PFOA, PFOS, and PFHxS concentrations and GWG, and a weak positive association between maternal PFNA and GWG.

Identifiants

DOI: 10.1016/j.reprotox.2019.08.003 PMID: 31415809 PMC: PMC6885527
pubmed: 31415809
pii: S0890-6238(19)30135-2
doi: 10.1016/j.reprotox.2019.08.003
pmc: PMC6885527
mid: NIHMS1048660
pii:
doi:

Substances chimiques

Alkanesulfonic Acids 0
Caprylates 0
Environmental Pollutants 0
Fatty Acids 0
Fluorocarbons 0
perfluoro-n-nonanoic acid 375-95-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

8-14

Subventions

Organisme : Medical Research Council
ID : MC_UU_00011/6
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_15018
Pays : United Kingdom
Organisme : Intramural CDC HHS
ID : CC999999
Pays : United States
Organisme : Medical Research Council
ID : G9815508
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 102215/2/13/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M009351/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_19009
Pays : United Kingdom

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Références

Crit Rev Toxicol. 2017 Jul;47(6):482-508
pubmed: 28617200
Reprod Toxicol. 2009 Jun;27(3-4):239-245
pubmed: 19429402
Int J Stat Med Res. 2015;4(3):287-295
pubmed: 27429686
Obes Rev. 2014 Apr;15(4):338-47
pubmed: 24321007
Epidemiology. 2018 Nov;29(6):765-776
pubmed: 30063543
Paediatr Perinat Epidemiol. 2018 Mar;32(2):152-160
pubmed: 29345321
Environ Int. 2018 Oct;119:515-526
pubmed: 30055518
Int J Obes (Lond). 2011 Jul;35(7):891-8
pubmed: 20975725
Int J Environ Res Public Health. 2016 Sep 12;13(9):
pubmed: 27626435
J Chromatogr A. 2011 Apr 15;1218(15):2133-7
pubmed: 21084089
Mol Cell Endocrinol. 2015 Jan 15;400:90-101
pubmed: 25448844
Child Obes. 2017 Jun;13(3):222-230
pubmed: 28128969
Environ Sci Technol. 2009 Jan 15;43(2):386-92
pubmed: 19238969
Environ Sci Technol. 2013 Sep 17;47(18):10619-27
pubmed: 23980546
Int J Epidemiol. 2002 Oct;31(5):1038-42
pubmed: 12435781
Environ Int. 2017 Sep;106:135-143
pubmed: 28645013
Int J Environ Res Public Health. 2016 Jan 20;13(1):null
pubmed: 26805861
Toxicology. 2011 Mar 15;281(1-3):48-55
pubmed: 21237237
Int J Hyg Environ Health. 2019 Jun;222(5):889-895
pubmed: 30975573
Nat Rev Endocrinol. 2015 Nov;11(11):653-61
pubmed: 26391979
Environ Health Perspect. 2007 Sep;115(9):1298-305
pubmed: 17805419
Am J Epidemiol. 1982 Aug;116(2):353-63
pubmed: 7114044
Environ Health Perspect. 2010 Feb;118(2):222-8
pubmed: 20123620
Int J Epidemiol. 2013 Feb;42(1):111-27
pubmed: 22507743
Curr Obes Rep. 2015 Sep;4(3):363-70
pubmed: 26627494
Am J Epidemiol. 2001 Aug 15;154(4):373-84
pubmed: 11495861
Am J Epidemiol. 2010 Dec 1;172(11):1306-14
pubmed: 20843863
Toxicol Sci. 2009 Feb;107(2):331-41
pubmed: 19005225
Environ Sci Technol. 2014 Aug 19;48(16):9600-8
pubmed: 25026485
Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105
pubmed: 19433254
Occup Environ Med. 2018 Jan;75(1):46-51
pubmed: 29133598
Environ Health Perspect. 2012 May;120(5):668-73
pubmed: 22306490
Environ Health Perspect. 2007 Nov;115(11):1596-602
pubmed: 18007991
Int J Epidemiol. 2013 Feb;42(1):97-110
pubmed: 22507742
Environ Int. 2013 Oct;60:242-8
pubmed: 24660230
Environ Res. 2008 Sep;108(1):56-62
pubmed: 18649879
Environ Health Perspect. 2007 Nov;115(11):1677-82
pubmed: 18008003
Int J Environ Res Public Health. 2018 Sep 21;15(10):
pubmed: 30241417
Br Heart J. 1995 Oct;74(4):449-54
pubmed: 7488463
Eur J Epidemiol. 2010 Mar;25(3):163-72
pubmed: 20127393
Environ Health Perspect. 2012 Oct;120(10):1432-7
pubmed: 22935244
Environ Sci Pollut Res Int. 2013 Nov;20(11):8031-44
pubmed: 23764977
Environ Health Perspect. 2007 Nov;115(11):1670-6
pubmed: 18008002
Am J Epidemiol. 2018 Apr 1;187(4):793-802
pubmed: 29155920
Toxicol Appl Pharmacol. 2004 Jul 15;198(2):231-41
pubmed: 15236955
Environ Int. 2011 Jan;37(1):129-35
pubmed: 20843552
J Chronic Dis. 1976 May;29(5):331-9
pubmed: 939796
Am J Clin Nutr. 2011 Jun;93(6):1285-92
pubmed: 21471282
J Expo Sci Environ Epidemiol. 2014 Sep-Oct;24(5):449-58
pubmed: 24424408
Mol Cell Endocrinol. 2009 May 25;304(1-2):19-29
pubmed: 19433244
Environ Health Perspect. 2014 Oct;122(10):1028-39
pubmed: 24968388
Reprod Toxicol. 2016 Oct;65:11-17
pubmed: 27319395
Environ Health Perspect. 2015 Dec;123(12):1317-24
pubmed: 26008903
Environ Sci Technol. 2006 Jan 1;40(1):32-44
pubmed: 16433330
Obstet Gynecol. 2010 Mar;115(3):597-604
pubmed: 20177292
Toxicology. 2003 Mar 3;184(2-3):135-40
pubmed: 12499116
Epidemiol Rev. 1987;9:1-30
pubmed: 3678409
Nutr Rev. 2013 Jun;71(6):343-52
pubmed: 23731445
Environ Health Perspect. 2004 Aug;112(11):1204-7
pubmed: 15289168
Anal Chem. 2005 Sep 15;77(18):6085-91
pubmed: 16159145
Am J Epidemiol. 2014 Mar 1;179(5):545-7
pubmed: 24401560
Toxicol Sci. 2007 Oct;99(2):366-94
pubmed: 17519394
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120

Auteurs

Kristin J Marks (KJ)

Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, Atlanta, GA 30322, United States; National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States. Electronic address: kristin.marks@emory.edu.

Zuha Jeddy (Z)

National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States; Oak Ridge Institute for Science and Education, 100 ORAU Way, Oak Ridge, TN 37830, United States.

W Dana Flanders (WD)

Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, Atlanta, GA 30322, United States; National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States.

Kate Northstone (K)

Department of Population Health Sciences, Bristol Medical School, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom.

Abigail Fraser (A)

Department of Population Health Sciences, Bristol Medical School, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom; The MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom.

Antonia M Calafat (AM)

National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States.

Kayoko Kato (K)

National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States.

Terryl J Hartman (TJ)

Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, Atlanta, GA 30322, United States; National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, United States.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Maternal serum concentrations of...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Acides du soufre › Acides sulfoniques › Acides alcanesulfoniques › Maternal serum concentrations of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Surveillance de l'environnement › Surveillance biologique › Maternal serum concentrations of...
questionsmedicales.fr › Lipides › Acides gras › Caprylates › Maternal serum concentrations of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Maternal serum concentrations of...
questionsmedicales.fr › Lipides › Acides gras › Maternal serum concentrations of...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures halogénés › Hydrocarbures fluorés › Fluorocarbones › Maternal serum concentrations of...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Prise de poids pendant la grossesse › Maternal serum concentrations of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Maternal serum concentrations of...
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Maternal serum concentrations of...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Maternal serum concentrations of...