ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer.
Animals
Carcinoma, Non-Small-Cell Lung
/ genetics
Cell Line, Tumor
Cell Proliferation
/ physiology
Heterografts
Humans
Kelch-Like ECH-Associated Protein 1
/ genetics
Lung Neoplasms
/ genetics
Mice
Mutation
NF-E2-Related Factor 2
/ metabolism
Receptor, ErbB-3
/ metabolism
Receptor, IGF Type 1
/ metabolism
Signal Transduction
/ physiology
Journal
Cancer research
ISSN: 1538-7445
Titre abrégé: Cancer Res
Pays: United States
ID NLM: 2984705R
Informations de publication
Date de publication:
01 Oct 2019
01 Oct 2019
Historique:
received:
08
07
2018
revised:
07
11
2018
accepted:
06
08
2019
pubmed:
17
8
2019
medline:
30
5
2020
entrez:
17
8
2019
Statut:
ppublish
Résumé
Mutations in
Identifiants
pubmed: 31416841
pii: 0008-5472.CAN-18-2086
doi: 10.1158/0008-5472.CAN-18-2086
doi:
Substances chimiques
IGF1R protein, human
0
KEAP1 protein, human
0
Kelch-Like ECH-Associated Protein 1
0
NF-E2-Related Factor 2
0
NFE2L2 protein, human
0
ERBB3 protein, human
EC 2.7.10.1
Receptor, ErbB-3
EC 2.7.10.1
Receptor, IGF Type 1
EC 2.7.10.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4828-4839Informations de copyright
©2019 American Association for Cancer Research.