A [13]rotaxane assembled via a palladium molecular capsule.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
16 08 2019
16 08 2019
Historique:
received:
10
04
2019
accepted:
22
07
2019
entrez:
18
8
2019
pubmed:
20
8
2019
medline:
20
8
2019
Statut:
epublish
Résumé
Molecules that are the size of small proteins are difficult to make. The most frequently examined route is via self-assembly, and one particular approach involves molecular nanocapsules, where ligands are designed that will enforce the formation of specific polyhedra of metals within the core of the structure. Here we show that this approach can be combined with mechanically interlocking molecules to produce nanocapsules that are decorated on their exterior. This could be a general route to very large molecules, and is exemplified here by the synthesis and structural characterization of a [13]rotaxane, containing 150 metal centres. Small angle X-ray scattering combined with atomistic molecular dynamics simulations demonstrate the compound is intact in solution.
Identifiants
pubmed: 31420545
doi: 10.1038/s41467-019-11635-6
pii: 10.1038/s41467-019-11635-6
pmc: PMC6697691
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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