Collateral Ventilation Measurement Using Chartis: Procedural Sedation vs General Anesthesia.
Anesthesia, General
/ methods
Bronchi
/ diagnostic imaging
Bronchoscopy
/ methods
Conscious Sedation
/ methods
Feasibility Studies
Female
Follow-Up Studies
Humans
Lung
/ diagnostic imaging
Male
Middle Aged
Prospective Studies
Pulmonary Emphysema
/ diagnosis
Pulmonary Ventilation
/ physiology
Tomography, X-Ray Computed
Treatment Outcome
Chartis measurement
collateral ventilation
endobronchial valve treatment
general anesthesia
procedural sedation
Journal
Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
08
05
2019
revised:
02
07
2019
accepted:
31
07
2019
pubmed:
20
8
2019
medline:
23
6
2020
entrez:
18
8
2019
Statut:
ppublish
Résumé
Absence of interlobar collateral ventilation is key to successful endobronchial valve treatment in patients with severe emphysema and can be functionally assessed by using the Chartis measurement. This system has been validated during spontaneous breathing, undergoing procedural sedation (PS), but can also be performed under general anesthesia. Performing the Chartis measurement under PS is often challenging because of coughing, mucus secretion, and difficulties in maintaining an adequate level of sedation. The objective of this study was to investigate whether there is a difference in Chartis measurement outcomes between PS and general anesthesia. In this prospective study, patients underwent Chartis measurements under both PS and general anesthesia. Study outcomes were Chartis measurement duration, number of measurements, feasibility, and success rate. The study included 30 patients with severe emphysema (mean age, 62 years; median FEV This study found that Chartis measurement under general anesthesia is faster and more feasible to perform compared with performance with PS, without affecting measurement outcomes. Clinicaltrials.gov; No. NCT03205826; URL: www.clinicaltrials.gov.
Sections du résumé
BACKGROUND
Absence of interlobar collateral ventilation is key to successful endobronchial valve treatment in patients with severe emphysema and can be functionally assessed by using the Chartis measurement. This system has been validated during spontaneous breathing, undergoing procedural sedation (PS), but can also be performed under general anesthesia. Performing the Chartis measurement under PS is often challenging because of coughing, mucus secretion, and difficulties in maintaining an adequate level of sedation. The objective of this study was to investigate whether there is a difference in Chartis measurement outcomes between PS and general anesthesia.
METHODS
In this prospective study, patients underwent Chartis measurements under both PS and general anesthesia. Study outcomes were Chartis measurement duration, number of measurements, feasibility, and success rate.
RESULTS
The study included 30 patients with severe emphysema (mean age, 62 years; median FEV
CONCLUSIONS
This study found that Chartis measurement under general anesthesia is faster and more feasible to perform compared with performance with PS, without affecting measurement outcomes.
TRIAL REGISTRATION
Clinicaltrials.gov; No. NCT03205826; URL: www.clinicaltrials.gov.
Identifiants
pubmed: 31421111
pii: S0012-3692(19)31455-2
doi: 10.1016/j.chest.2019.07.025
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT03205826']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
984-990Informations de copyright
Copyright © 2019 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.