[First-episode psychosis as primary manifestation of medical disease: An update].

Premier épisode psychotique révélant une affection médicale générale : mise au point pour l’interniste.

Journal

La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 21 02 2019
revised: 09 06 2019
accepted: 17 07 2019
pubmed: 20 8 2019
medline: 7 5 2020
entrez: 19 8 2019
Statut: ppublish

Résumé

A huge variety of medical diseases may potentially present with isolated psychotic symptoms, and disease-specific treatment or management is available for a significant part of them. The initial medical work-up of a first-episode psychosis (FEP) is of crucial importance. This literature review aimed to identify medical conditions potentially revealed by FEP, to list the warning signs of secondary psychosis, and to discuss a screening strategy. Underlying organic conditions may be drugs and medications, neurologic diseases, infections, inflammatory and/or autoimmune pathologies, and metabolic disorders whether of hereditary origin. Each patient presenting with a first-episode psychosis should be evaluated with a precise anamnesis, a careful clinical examination, and routine laboratory tests. Brain imaging and tests (depending on the context) should be performed in the presence of atypical clinical features or "red flags", leading to suspect an organic disease.

Identifiants

pubmed: 31421899
pii: S0248-8663(19)30607-1
doi: 10.1016/j.revmed.2019.07.006
pii:
doi:

Types de publication

Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

742-749

Informations de copyright

Copyright © 2019. Published by Elsevier Masson SAS.

Auteurs

J Goutte (J)

Service de médecine interne, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: julie.goutte@chu-st-etienne.fr.

M Killian (M)

Service de médecine interne, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: martin.killian@chu-st-etienne.fr.

J C Antoine (JC)

Service de neurologie, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: j.christophe.antoine@chu-st-etienne.fr.

C Massoubre (C)

Service de psychiatrie, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: catherine.massoubre@chu-st-etienne.fr.

E Fakra (E)

Service de psychiatrie, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: eric.fakra@chu-st-etienne.fr.

P Cathébras (P)

Service de médecine interne, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France. Electronic address: pascal.cathebras@chu-st-etienne.fr.

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Classifications MeSH