Sexual function recovery after robot-assisted radical prostatectomy: Outcomes from an Italian referral centre and predicting nomogram.
Aged
Feasibility Studies
Humans
Italy
Male
Middle Aged
Nomograms
Postoperative Period
Prostate
/ surgery
Prostatectomy
/ methods
Prostatic Neoplasms
/ physiopathology
Quality of Life
Recovery of Function
/ physiology
Robotic Surgical Procedures
/ methods
Sexual Behavior
/ physiology
Surveys and Questionnaires
/ statistics & numerical data
Treatment Outcome
nomogram
prostate cancer
robotic prostatectomy
sexual function
Journal
Andrologia
ISSN: 1439-0272
Titre abrégé: Andrologia
Pays: Germany
ID NLM: 0423506
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
16
05
2019
revised:
20
06
2019
accepted:
10
07
2019
pubmed:
20
8
2019
medline:
3
4
2020
entrez:
20
8
2019
Statut:
ppublish
Résumé
Aims of this study were to assess sexual recovery after robotic-assisted radical prostatectomy (RARP) and to build a nomogram predicting 1-year sexual function. From May 2015 to July 2016, all patients eligible for RARP at our institution were invited to enter the study. The Expanded Prostate cancer Index Composite (EPIC) questionnaire was administered pre-operatively, then at 45 days, and at 3, 6, 9, and 12 months post-operatively. According to sexual function scores, patients were divided into four classes. Multivariate analysis was used to investigate the influence of patient- and disease-related features on sexual recovery. A total of 643 patients were included. Age was associated with baseline potency (p < .0001). Bioptic Gleason score (GS; p = .0002), American Society of Anesthesiologists (ASA) score ( = .002ASA Physical Status Classification System ) and Charlson Comorbidity Index (CCI; p = .02) were negatively associated with potency. Baseline sexual function was associated with potency recovery. A nomogram resulted from fitting a proportional odds logistic model for ordinal outcomes, with 1-year sexual function as a dependent variable and baseline sexual potency, age, body mass index (BMI), clinical stage, biopsy GS, initial prostate-specific antigen (iPSA), ASA score, and CCI as predictors. After further validation, this nomogram could be a useful tool for the pre-operative counselling.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13385Informations de copyright
© 2019 Blackwell Verlag GmbH.
Références
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