Hysteroscopic Evaluation of Endometrial Changes in Breast Cancer Women with or without Hormone Therapies: Results from a Large Multicenter Cohort Study.

Adult Aged Aged, 80 and over Antineoplastic Agents, Hormonal / therapeutic use Biopsy Breast Neoplasms / diagnostic imaging Cohort Studies Endometrial Hyperplasia / diagnosis Endometrial Neoplasms / diagnosis Endometrium / diagnostic imaging Female Humans Hysteroscopy / methods Incidence Middle Aged Polyps / diagnosis Precancerous Conditions / diagnosis Pregnancy Retrospective Studies Tamoxifen / therapeutic use Uterine Diseases / diagnosis Uterine Neoplasms / diagnosis
Aromatase inhibitors Breast cancer Endometrial cancer Endometrial pathologies Tamoxifen

Journal

Journal of minimally invasive gynecology
ISSN: 1553-4669
Titre abrégé: J Minim Invasive Gynecol
Pays: United States
ID NLM: 101235322

Informations de publication

Date de publication:
Historique:
received: 15 04 2019
revised: 30 07 2019
accepted: 04 08 2019
pubmed: 20 8 2019
medline: 6 1 2021
entrez: 20 8 2019
Statut: ppublish

Résumé

The primary aim of our study was to investigate the incidence of endometrial pathologies, especially endometrial cancer, in women with breast cancer treated with tamoxifen (TAM), aromatase inhibitors (AIs), or receiving no treatment (NT). The secondary aim was to identify, in this cohort, ultrasonographic findings that represent robust indications for hysteroscopy and endometrial biopsy, to avoid unnecessary second-level diagnostic procedures. Multicenter retrospective cohort study (Clinical Trial ID: NCT03898947). Data were collected from different Italian centers: Regina Elena National Cancer Institute of Rome, Arbor Vitae Centre of Rome, Gaetano Martino University Hospital of Messina, and Villa Sofia-Cervello Hospital of Palermo. We selected and consecutively included patients with a history of breast cancer who had undergone hysteroscopy for ultrasonographic or clinical indications between January 2007 and December 2016. Diagnostic hysteroscopy with endometrial biopsy or operative hysteroscopy, when clinically indicated. A higher percentage of patients in the TAM and AI groups had a normal endometrium compared with those in the NT group, whereas the incidence of endometrial polyps was higher in the NT group than in the others; no significant differences were observed among the 3 groups for other benign conditions or for premalignant and malignant uterine diseases, such as endometrial atypical hyperplasia and adenocarcinoma. TAM treatment does not seem to be associated with a higher rate of endometrial cancer in women with breast cancer compared with women treated with AIs or NT.

Identifiants

DOI: 10.1016/j.jmig.2019.08.007 PMID: 31425735
pubmed: 31425735
pii: S1553-4650(19)30365-6
doi: 10.1016/j.jmig.2019.08.007
pii:
doi:

Substances chimiques

Antineoplastic Agents, Hormonal 0
Tamoxifen 094ZI81Y45

Banques de données

ClinicalTrials.gov
['NCT03898947']

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

832-839

Informations de copyright

Copyright © 2019 AAGL. Published by Elsevier Inc. All rights reserved.

Auteurs

Benito Chiofalo (B)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Ivano Mazzon (I)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Silvia Di Angelo Antonio (S)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Donatella Amadore (D)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Enrico Vizza (E)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Antonio Simone Laganà (AS)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti). Electronic address: antoniosimone.lagana@uninsubria.it.

Giuseppe Vocaturo (G)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Gloria Calagna (G)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Alessandro Favilli (A)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Vittorio Palmara (V)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Marianna Maranto (M)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Salvatore Giovanni Vitale (SG)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Gaspare Cucinella (G)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Roberta Granese (R)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Fabio Ghezzi (F)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Isabella Sperduti (I)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

Onofrio Triolo (O)

Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Drs. Chiofalo, Vizza, and Vocaturo); Arbor Vitae Centre, Nuova Villa Claudia Clinic, Rome, Italy (Drs. Mazzon and Di Angelo Antonio); Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi," University of Messina, Messina, Italy (Drs. Amadore, Palmara, Granese, and Triolo); Department of Obstetrics and Gynecology, Filippo Del Ponte Hospital, University of Insubria, Varese, Italy (Drs. Laganà and Ghezzi); Gynecology and Obstetrics Unit, Villa Sofia-Cervello Hospital, University of Palermo, Palermo, Italy (Drs. Calagna, Maranto, and Cucinella); Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Dr. Favilli); Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy (Dr.Vitale); Biostatistical Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy (Dr. Sperduti).

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antinéoplasiques hormonaux › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytodiagnostic › Biopsie › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Maladies urogénitales › Maladies génitales › Maladies de l'appareil génital féminin › Maladies de l'utérus › Hyperplasie endométriale › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital féminin › Tumeurs de l'utérus › Tumeurs de l'endomètre › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Appareil urogénital › Système génital › Système génital de la femme › Utérus › Endomètre › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie urogénitale › Procédures de chirurgie gynécologique › Hystéroscopie › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Incidence › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › États, signes et symptômes pathologiques › États anatomopathologiques › Polypes › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Tumeurs › États précancéreux › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Composés benzylidéniques › Stilbènes › Tamoxifène › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Maladies urogénitales › Maladies génitales › Maladies de l'appareil génital féminin › Maladies de l'utérus › Hysteroscopic Evaluation of Endometrial...
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital féminin › Tumeurs de l'utérus › Hysteroscopic Evaluation of Endometrial...