Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals.


Journal

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 24 05 2019
accepted: 11 08 2019
pubmed: 21 8 2019
medline: 29 9 2020
entrez: 21 8 2019
Statut: ppublish

Résumé

Infection by Toxoplasma gondii is prevalent worldwide. The parasite can infect a broad spectrum of vertebrate hosts, but infection of fetuses and immunocompromised patients is of particular concern. Easy-to-perform, robust, and highly sensitive and specific methods to detect Toxoplasma infection are important for the treatment and management of patients. Rapid diagnostic methods that do not sacrifice the accuracy of the assay and give reproducible results in a short time are highly desirable. In this context, rapid diagnostic tests (RDTs), especially with point-of-care (POC) features, are promising diagnostic methods in clinical microbiology laboratories, especially in areas with minimal laboratory facilities. More advanced methods using microfluidics and sensor technology will be the future trend. In this review, we discuss serological and molecular-based rapid diagnostic tests for detecting Toxoplasma infection in humans as well as animals.

Identifiants

pubmed: 31428897
doi: 10.1007/s10096-019-03680-2
pii: 10.1007/s10096-019-03680-2
pmc: PMC7087738
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

19-30

Subventions

Organisme : Malaysian Ministry of Education
ID : HICoE No. 311/CIPPM/4401005

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Auteurs

Amjad Hayat Khan (AH)

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800, Minden, Penang, Malaysia.

Rahmah Noordin (R)

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800, Minden, Penang, Malaysia. rahmah8485@gmail.com.

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