Novel ionization reagent for the measurement of gas-phase ammonia and amines using a stand-alone atmospheric pressure gas chromatography (APGC) source.
Journal
Rapid communications in mass spectrometry : RCM
ISSN: 1097-0231
Titre abrégé: Rapid Commun Mass Spectrom
Pays: England
ID NLM: 8802365
Informations de publication
Date de publication:
30 May 2020
30 May 2020
Historique:
received:
21
12
2018
revised:
14
08
2019
accepted:
14
08
2019
pubmed:
21
8
2019
medline:
21
8
2019
entrez:
21
8
2019
Statut:
ppublish
Résumé
Contaminants present in ambient air or in sampling lines can interfere with the target analysis through overlapping peaks or causing a high background. This study presents a positive outcome from the unexpected presence of N-methyl-2-pyrrolidone, released from a PALL HEPA filter, in the analysis of atmospherically relevant gas-phase amines using chemical ionization mass spectrometry. Gas-phase measurements were performed using a triple quadrupole mass spectrometer equipped with a modified atmospheric pressure gas chromatography (APGC) source which allows sampling of the headspace above pure amine standards. Gas-phase N-methyl-2-pyrrolidone (NMP) emitted from a PALL HEPA filter located in the inlet stream served as the ionizing agent. This study demonstrates that some alkylamines efficiently form a [NMP + amine+H] The use of NMP as an ionizing agent with stand-alone APGC provided high sensitivity for ammonia and the smaller amines. The main advantages, in addition to sensitivity, are direct sampling into the APGC source and avoiding uptake on sampling lines which can be a significant problem with ammonia and amines.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e8561Subventions
Organisme : Army Research Office
ID : W911NF1710105
Organisme : National Science Foundation
ID : 1443140
Organisme : National Science Foundation
ID : 1710580
Organisme : National Science Foundation
ID : 1710691
Organisme : NSF Major Research Instrumentation (MRI)
ID : 1337080
Informations de copyright
© 2019 John Wiley & Sons, Ltd.
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