Nonpharmacological interventions for the prevention of hypertension in low- and middle-income countries: a systematic review and meta-analysis.


Journal

Journal of human hypertension
ISSN: 1476-5527
Titre abrégé: J Hum Hypertens
Pays: England
ID NLM: 8811625

Informations de publication

Date de publication:
11 2019
Historique:
received: 22 01 2019
accepted: 17 06 2019
revised: 18 03 2019
pubmed: 23 8 2019
medline: 4 9 2020
entrez: 22 8 2019
Statut: ppublish

Résumé

Hypertension is the single biggest cause of various cardiovascular complications and at the same time one of the most preventable phenomena. Low- and middle-income countries (LMICs) are facing increasing prevalence of hypertension which is imposing a huge burden on morbidity, premature mortality, and catastrophic health expenditure. This systematic review searched for the nonpharmacological interventions for prevention of hypertension among normotensive people in LMICs considering the period 1990-2016. This review has been conducted following standard methodology of Cochrane review involving two independent reviewers in screening, quality appraisal, and data extraction. Narrative synthesis of included articles was demonstrated using tables and meta-analysis was conducted to pool the estimates of studies which fulfilled the criteria. Total seven trials were included in the review with 6046 participants from eight LMICs. Two cluster randomized trials were pooled and there was a statistically significant effect (Systolic Blood Pressure: mean difference -2.35 [95% CI: -4.31 to -0.38], Diastolic Blood Pressure: mean difference -2.11 [95% CI: -3.20 to -1.02]) of home based health education in reducing blood pressure. Three individual studies reported reduction of blood pressure as a result of restricted dietary sodium intake. None of the studies was appraised as low risk of bias due to poor methodological quality. Non-pharmacological interventions can play important role in preventing the development of hypertension among normotensive people. Further trials with longer follow-up period and robust methods are recommended for getting stronger evidence on these interventions.

Identifiants

pubmed: 31431679
doi: 10.1038/s41371-019-0223-x
pii: 10.1038/s41371-019-0223-x
pmc: PMC6892411
doi:

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

786-794

Références

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Auteurs

K M Saif-Ur-Rahman (KM)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh. su.rahman@icddrb.org.
Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. su.rahman@icddrb.org.

Syed Shariful Islam (S)

Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Md Hasan (M)

Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Shahed Hossain (S)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.
James P. Grant School of Public Health, BRAC University, Dhaka, Bangladesh.

Razib Mamun (R)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.
Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Sohana Shafique (S)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.

Al Mamun (A)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.

Md Khalequzzaman (M)

Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Fariha Haseen (F)

Systematic Review Centre (SRC), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Aminur Rahman (A)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.

Iqbal Anwar (I)

Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh.

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