Elective neck dissection for the node-negative neck during salvage laryngectomy: an analysis of survival outcomes and complication rates.

Laryngectomy Neck Dissection Salvage Therapy Surgical Oncology

Journal

The Journal of laryngology and otology
ISSN: 1748-5460
Titre abrégé: J Laryngol Otol
Pays: England
ID NLM: 8706896

Informations de publication

Date de publication:
Sep 2019
Historique:
pubmed: 23 8 2019
medline: 23 8 2019
entrez: 23 8 2019
Statut: ppublish

Résumé

This study aimed to evaluate the effect of neck dissection on survival and complication rates in patients with no clinical or radiological evidence of cervical nodal disease (N0) undergoing salvage laryngectomy. A retrospective study was conducted of patients with squamous cell carcinoma of the larynx following primary radiotherapy that required salvage laryngectomy. Disease-free and overall survival rates were compared over three years using Kaplan-Meier analysis. Pharyngocutaneous fistula rate, hospitalisation length and the requirement for further surgical intervention were also compared across cohorts. Twenty-three cases met the inclusion criteria (17 neck dissections, 6 undissected). No significant differences in survival outcomes were identified. One patient who underwent neck dissection for advanced, recurrent transglottic squamous cell carcinoma showed evidence of occult lymph node metastases. Fistula rates did not differ significantly between dissected and non-dissected groups; however, two patients required surgical repair of post-operative pharyngocutaneous fistula following neck dissection. In this study, elective neck dissection did not appear to alter survival outcomes or complication rates during salvage laryngectomy. Given the small but significant risk of occult neck metastases, its true value remains unclear.

Identifiants

pubmed: 31434593
doi: 10.1017/S0022215119001725
pii: S0022215119001725
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

788-791

Auteurs

M Gouzos (M)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

O Dale (O)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

N Sethi (N)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

A Foreman (A)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

S Krishnan (S)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

J C Hodge (JC)

Department of Otolaryngology - Head and Neck Surgery, Royal Adelaide Hospital, Australia.

Classifications MeSH