Interleukins in diagnosis of perinatal asphyxia: A systematic review.
Asphyxia neonatorum.
Interleukins
Diagnosis
Journal
International journal of reproductive biomedicine
ISSN: 2476-4108
Titre abrégé: Int J Reprod Biomed
Pays: Iran
ID NLM: 101679102
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
20
12
2017
revised:
25
03
2018
accepted:
12
09
2018
entrez:
23
8
2019
pubmed:
13
6
2018
medline:
13
6
2018
Statut:
epublish
Résumé
Biochemical markers including interleukins (ILs) has been proposed for early diagnosis of asphyxia. This study has aimed to systematically review the significance of IL measurements in the diagnosis of perinatal asphyxia. PubMed, Cochrane Library, Web of Science, Embase, and Scopus databases before 2017 were searched for the following keywords: asphyxia, neonatal, interleukin, and diagnosis. A total of 13 out of 300 searched papers were finally selected for evaluation. Interleukins under study were IL6 and interleukin 1 Research on the issue suggests that IL6 > 41 Pg/dl has the sensitivity of 84.88% and the specificity of 85.43%, whereas IL-1 IL6 and IL-1
Sections du résumé
BACKGROUND
BACKGROUND
Biochemical markers including interleukins (ILs) has been proposed for early diagnosis of asphyxia.
OBJECTIVE
OBJECTIVE
This study has aimed to systematically review the significance of IL measurements in the diagnosis of perinatal asphyxia.
MATERIALS AND METHODS
METHODS
PubMed, Cochrane Library, Web of Science, Embase, and Scopus databases before 2017 were searched for the following keywords: asphyxia, neonatal, interleukin, and diagnosis. A total of 13 out of 300 searched papers were finally selected for evaluation. Interleukins under study were IL6 and interleukin 1
RESULTS
RESULTS
Research on the issue suggests that IL6 > 41 Pg/dl has the sensitivity of 84.88% and the specificity of 85.43%, whereas IL-1
CONCLUSION
CONCLUSIONS
IL6 and IL-1
Identifiants
pubmed: 31435616
doi: 10.18502/ijrm.v17i5.4598
pmc: PMC6653496
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
J Clin Invest. 1998 Jan 15;101(2):311-20
pubmed: 9435302
Neurosci Lett. 1996 Feb 2;204(1-2):109-12
pubmed: 8929990
Arch Iran Med. 2010 Jul;13(4):275-81
pubmed: 20597559
Pediatrics. 2002 Oct;110(4):673-80
pubmed: 12359779
Stroke. 2000 Oct;31(10):2325-9
pubmed: 11022058
J Pediatr (Rio J). 2003 Jul-Aug;79(4):297-302
pubmed: 14513127
Immunol Lett. 1989 May;21(2):177-84
pubmed: 2548955
J Immunol. 1990 Jan 1;144(1):129-35
pubmed: 2104886
J Matern Fetal Neonatal Med. 2017 Nov;30(21):2551-2556
pubmed: 27809621
Pediatrics. 1997 Nov;100(5):789-94
pubmed: 9346977
Arch Iran Med. 2016 May;19(5):312-6
pubmed: 27179161
Iran J Pediatr. 2015 Aug;25(4):e2006
pubmed: 26396695
J Cereb Blood Flow Metab. 2012 Oct;32(10):1888-96
pubmed: 22805873
Biol Neonate. 2006;89(3):183-9
pubmed: 16244469
Pediatr Res. 1996 Oct;40(4):603-9
pubmed: 8888290
Pediatr Neurol. 2004 Nov;31(5):326-32
pubmed: 15519113
Arch Dis Child Fetal Neonatal Ed. 1998 Nov;79(3):F190-3
pubmed: 10194989
J Trop Pediatr. 2010 Jun;56(3):178-82
pubmed: 19822562
Brain Res. 2001 Jan 19;889(1-2):165-73
pubmed: 11166700
Exp Ther Med. 2014 Oct;8(4):1259-1262
pubmed: 25187835
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F1-3
pubmed: 8092861
Brain Dev. 2006 Apr;28(3):178-82
pubmed: 16181755
Eur J Clin Invest. 2003 Apr;33(4):352-8
pubmed: 12662167
Curr Opin Pediatr. 1999 Dec;11(6):487-91
pubmed: 10590904
Semin Pediatr Neurol. 1998 Sep;5(3):190-201
pubmed: 9777677
Pediatrics. 2002 Jan;109(1):26-33
pubmed: 11773538
J Cereb Blood Flow Metab. 2009 Mar;29(3):464-79
pubmed: 19018268
Pediatr Neonatol. 2012 Dec;53(6):334-9
pubmed: 23276436
Biol Neonate. 2001;79(3-4):213-8
pubmed: 11275654
Iran J Pediatr. 2015 Apr;25(2):e381
pubmed: 26196004
Pediatr Res. 1997 Jul;42(1):1-8
pubmed: 9212029
Pediatr Res. 1998 Jun;43(6):746-51
pubmed: 9621983
Exp Neurol. 1994 Dec;130(2):362-7
pubmed: 7867766
Am J Obstet Gynecol. 2000 Mar;182(3):675-81
pubmed: 10739529
Int J Hematol. 2001 Jul;74(1):3-8
pubmed: 11530802