Chlamydia psittaci infection as a cause of respiratory disease in neonatal foals.
Chlamydia psittaci
acute lung injury
acute respiratory distress syndrome
atypical pneumonia
horse
Journal
Equine veterinary journal
ISSN: 2042-3306
Titre abrégé: Equine Vet J
Pays: United States
ID NLM: 0173320
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
20
05
2019
accepted:
15
08
2019
pubmed:
23
8
2019
medline:
2
7
2020
entrez:
23
8
2019
Statut:
ppublish
Résumé
During 2016-2018, 15 critically ill neonatal foals with acute respiratory distress associated with Chlamydia psittaci infection were presented to three referral hospitals in New South Wales. Chlamydia psittaci has not previously been associated with the development of neonatal respiratory disease. To investigate and describe the clinical features and outcome of C. psittaci infection in neonatal foals. Multicentre retrospective case series. The clinical, clinicopathological, necropsy and histological features of 15 foals with confirmed C. psittaci infection were reviewed and reported. Thirteen foals with C. psittaci infection died or were subjected to euthanasia within 36 h of hospitalisation and two foals survived to discharge. Findings during post-mortem examination of nonsurviving foals included bronchopneumonia, pulmonary congestion, hepatic congestion and hepatic inflammation. Detection of C. psittaci was achieved using polymerase chain reaction (PCR) testing of swabs of nasal secretions (4/6) and rectal mucosa (5/7) from live foals, lung tissues of foals at necropsy (11/14) and foetal membranes (4/5). Small numbers of confirmed cases of neonatal C. psittaci infection and inconsistent sampling methods. Chlamydia psittaci should be considered a differential diagnosis for neonatal foals with signs of severe systemic disease, including equine neonatal acute respiratory distress syndrome (EqNARDS). Chlamydia psittaci is a zoonotic pathogen and a personal protective equipment (PPE) should be worn for the management of foals with suspected or confirmed infection.
Sections du résumé
BACKGROUND
BACKGROUND
During 2016-2018, 15 critically ill neonatal foals with acute respiratory distress associated with Chlamydia psittaci infection were presented to three referral hospitals in New South Wales. Chlamydia psittaci has not previously been associated with the development of neonatal respiratory disease.
OBJECTIVES
OBJECTIVE
To investigate and describe the clinical features and outcome of C. psittaci infection in neonatal foals.
STUDY DESIGN
METHODS
Multicentre retrospective case series.
METHODS
METHODS
The clinical, clinicopathological, necropsy and histological features of 15 foals with confirmed C. psittaci infection were reviewed and reported.
RESULTS
RESULTS
Thirteen foals with C. psittaci infection died or were subjected to euthanasia within 36 h of hospitalisation and two foals survived to discharge. Findings during post-mortem examination of nonsurviving foals included bronchopneumonia, pulmonary congestion, hepatic congestion and hepatic inflammation. Detection of C. psittaci was achieved using polymerase chain reaction (PCR) testing of swabs of nasal secretions (4/6) and rectal mucosa (5/7) from live foals, lung tissues of foals at necropsy (11/14) and foetal membranes (4/5).
MAIN LIMITATIONS
CONCLUSIONS
Small numbers of confirmed cases of neonatal C. psittaci infection and inconsistent sampling methods.
CONCLUSIONS
CONCLUSIONS
Chlamydia psittaci should be considered a differential diagnosis for neonatal foals with signs of severe systemic disease, including equine neonatal acute respiratory distress syndrome (EqNARDS). Chlamydia psittaci is a zoonotic pathogen and a personal protective equipment (PPE) should be worn for the management of foals with suspected or confirmed infection.
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
244-249Subventions
Organisme : Charles Sturt University
Informations de copyright
© 2019 EVJ Ltd.
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