Atrial Tachycardia With Atrial Activation Duration Exceeding the Tachycardia Cycle Length: Mechanisms and Prevalence.


Journal

JACC. Clinical electrophysiology
ISSN: 2405-5018
Titre abrégé: JACC Clin Electrophysiol
Pays: United States
ID NLM: 101656995

Informations de publication

Date de publication:
08 2019
Historique:
received: 05 11 2018
revised: 23 04 2019
accepted: 25 04 2019
entrez: 24 8 2019
pubmed: 24 8 2019
medline: 24 10 2020
Statut: ppublish

Résumé

This study sought to identify atrial tachycardia (AT) demonstrating atrial activation duration (AAD) lasting longer than the length of the tachycardia cycle (TCL); to assess AT prevalence; and to evaluate the mechanisms and characteristics associated with these AT episodes by using the Rhythmia system (Boston Scientific, Marlborough, Massachusetts). Ultra-high-density mapping allows very accurate characterization of mechanisms involved in AT. Some complex patterns may involve AAD which is longer than the tachycardia cycle length (TCL) which makes maps difficult to interpret. Prevalence and characteristics of such ATs are unknown. A cohort of 100 consecutive patients undergoing ablation of 125 right (n = 21) or left (n = 104) ATs using ultra-high-density mapping were retrospectively included. Offline calculation of right or left AAD was compared to TCL. Mean TCL was 293 ± 65 ms, and mean AAD was 291 ± 74 ms (p = NS). AT mechanisms were macro-re-entry in 74 cases (59%), localized re-entry in 27 cases (22%), and focal AT in 21 cases (17%) (types were mixed in 3 cases). Fifteen ATs (12%) had AADs that were longer than the TCL (71 ± 45 ms longer, from 10 to 150 ms). TCL was equal to the AAD in 97 ATs (78%), whereas 13 ATs (10%) had AAD shorter than the TCL (focal AT in each case). There were no differences between right and left atria for prevalence of ATs with AADs that were longer than the TCLs. There were significant differences in AT mechanisms according to the AAD-to-TCL ratio (p < 0.0001), with localized re-entry showing more often that AAD was longer than the TCL compared to that in focal AT and macro-re-entry. ATs with AAD lasting longer than the TCL were present in approximately 10% of the ATs referred for ablation, mostly in ATs caused by localized re-entry. Ultra-high-density mapping allows detection of these complex patterns of activation.

Sections du résumé

OBJECTIVES
This study sought to identify atrial tachycardia (AT) demonstrating atrial activation duration (AAD) lasting longer than the length of the tachycardia cycle (TCL); to assess AT prevalence; and to evaluate the mechanisms and characteristics associated with these AT episodes by using the Rhythmia system (Boston Scientific, Marlborough, Massachusetts).
BACKGROUND
Ultra-high-density mapping allows very accurate characterization of mechanisms involved in AT. Some complex patterns may involve AAD which is longer than the tachycardia cycle length (TCL) which makes maps difficult to interpret. Prevalence and characteristics of such ATs are unknown.
METHODS
A cohort of 100 consecutive patients undergoing ablation of 125 right (n = 21) or left (n = 104) ATs using ultra-high-density mapping were retrospectively included. Offline calculation of right or left AAD was compared to TCL.
RESULTS
Mean TCL was 293 ± 65 ms, and mean AAD was 291 ± 74 ms (p = NS). AT mechanisms were macro-re-entry in 74 cases (59%), localized re-entry in 27 cases (22%), and focal AT in 21 cases (17%) (types were mixed in 3 cases). Fifteen ATs (12%) had AADs that were longer than the TCL (71 ± 45 ms longer, from 10 to 150 ms). TCL was equal to the AAD in 97 ATs (78%), whereas 13 ATs (10%) had AAD shorter than the TCL (focal AT in each case). There were no differences between right and left atria for prevalence of ATs with AADs that were longer than the TCLs. There were significant differences in AT mechanisms according to the AAD-to-TCL ratio (p < 0.0001), with localized re-entry showing more often that AAD was longer than the TCL compared to that in focal AT and macro-re-entry.
CONCLUSIONS
ATs with AAD lasting longer than the TCL were present in approximately 10% of the ATs referred for ablation, mostly in ATs caused by localized re-entry. Ultra-high-density mapping allows detection of these complex patterns of activation.

Identifiants

pubmed: 31439291
pii: S2405-500X(19)30334-2
doi: 10.1016/j.jacep.2019.04.015
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

907-916

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Auteurs

Philippe Maury (P)

Department of Cardiology, University Hospital Rangueil, Toulouse, France; Unité Inserm U 1048, Toulouse, France. Electronic address: mauryjphil@hotmail.com.

Masateru Takigawa (M)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Stefano Capellino (S)

Boston Scientific, Voisin Le Bretonneux, France.

Anne Rollin (A)

Department of Cardiology, University Hospital Rangueil, Toulouse, France.

Jean Rodolphe Roux (JR)

Boston Scientific, Voisin Le Bretonneux, France.

Pierre Mondoly (P)

Department of Cardiology, University Hospital Rangueil, Toulouse, France.

Franck Mandel (F)

Department of Cardiology, University Hospital Rangueil, Toulouse, France.

Benjamin Monteil (B)

Department of Cardiology, University Hospital Rangueil, Toulouse, France.

Arnaud Denis (A)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Frederic Sacher (F)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Meleze Hocini (M)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Michel Haïssaguerre (M)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Nicolas Derval (N)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

Pierre Jaïs (P)

Department of Cardiology, University Hospital Haut-Lévèque, Pessac, France; LIRYC Institute/INSERM 1045, Bordeaux University Hospital, Bordeaux, France.

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